Lucine

Lucine Research Featured in International Innovation

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Data decisions discovery

Lucine Health Sciences, the parent company of Hormones MatterTM and Heal with FriendsTM, was featured in a recent piece on women’s health, in International Innovation. Entitled Data, Decisions and Discovery, the article is a first in a series of articles that will highlight our unique approach to research. From the article:

Medical science was, and still is to some degree, predicated upon physicians and researchers having a controlling view of patient health. Among scientists, there is a tendency to favour pristine and highly controlled experiments that address just one variable at a time. Yet while this may result in neat, publishable studies, it fails to take into account the complexities of life and human physiology. “When you isolate one variable at a time, you may obtain some interesting insights into the operation of that variable – but this does not address the complexity of  the systems in human health and disease,” Marrs elucidates. “Science will only move forwards if we successfully capture the messiness of multiple variables and understand how they interact with each other within the context of health and disease.”

For modern research to be effective, it must take into account the patient’s knowledge about his or her health and move beyond the paradigm that equates health with simple linear equations. By putting the patient at the centre of the research equation and considering multiple variables, Lucine Health Sciences is well-placed to explore the efficacy of medications, as well as their potential side effects.

To read the full article: Data, Decisions and Discovery.

About Lucine Health Sciences

Lucine Health Sciences is a social-benefit company committed to improving healthcare by providing critical and credible health information to consumers, physicians and industry. We leverage the broad social media reach generated by Hormones MatterTM to conduct large-scale and much needed research in the field of women’s health. Studies address the side effects associated with common medications, vaccines and surgical procedures used in women’s healthcare. Contract research services are available.

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Thank You Lucine Supporters

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Last week Lucine entered a grant competition – Mission Small Business, that required us to collect 250 online votes for Lucine Biotechnology. After 2.5 days, we reached our goal and qualified for the next step – the review.

The Lucine Team would like to thank all of our supporters who took the time out their busy schedules to vote for us. We would especially like to thank those supporters who not only voted for us, but advocated for Lucine by posting our requests on the various social networks. We had support from England, Norway, Poland and across the US. In Southern Nevada #vegastech was instrumental in rallying the Twittersphere. Thank you Lucine Supporters.

The results of the Mission Small Business grant competition will be announced September 15. We’ll keep you posted.

 

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Avoidable Ignorance: Implications for Women’s Health

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It is difficult to read the stories of suffering expressed by the women featured in our blog and not become incensed. We can joke about women’s hormone health and deride the science to fringe status, but our failure to recognize, investigate and create options for women has serious consequences. In my mind, this is an avoidable ignorance.

I borrowed that phrase from a quote by Dr. Albert G. Mulley, the new Director of the Dartmouth Center for Health Care Delivery Science. The full quote “no decision should be made in the face of avoidable ignorance” speaks volumes about the state of women’s health care.

How many women have sought treatment for a dysregulated menstrual cycle, menstrual cycle related pain, or other presumably hormonally modulated events only to be sent home without so much as a lab test but with oral contraceptives? Worse yet, how many women have had an endless array of invasive procedures only to receive an uncertain diagnosis and oral contraceptives. This is avoidable ignorance.

Why don’t women get routine hormone testing for what are presumably hormone related conditions? We wouldn’t treat high blood pressure without first measuring blood pressure or diabetes without first measuring glucose. Why then would we treat presumably hormonal conditions, with hormone modifying drugs, without ever measuring hormones before or during treatment? Is the pill so successful at treating all female symptoms that no testing is ever needed? Or is there some avoidable ignorance at play? Judge for yourself.

The most common arguments against hormone testing include:

1. The clinical reference ranges for hormones are too broad to be useful
2. The test results will not modify clinical decision making, so why test
3. Hormones are too complicated and variable
4. A good clinical interview suffices

It’s not that we cannot develop more robust hormone reference ranges, more sensitive hormone testing methods, perhaps link a woman’s unique biochemistry to her clinical symptoms, we just have not. The often repeated excuse that ‘hormones are complicated, variable and too difficult to analyze’ just doesn’t hold true given the state of science and technology today, neither does the clinical interview argument. A good clinical interview is always important and maybe even a lost art in this era of high tech diagnostics, but wouldn’t it be nice if the average time to diagnose some of these conditions wasn’t 5-10 years?

This brings me back to Dr. Mulley and his discussion on ending avoidable ignorance in healthcare. The responsibility, Dr. Mulley contends, rests with the patient. As a supporter of the e-patient movement, Dr. Mulley believes patients have the responsibility to educate the physicians and other decision-makers about what’s important to them. He says “unless we know what you care about, we have no information to inform investment or disinvestment” in any particular area of health.

In this context, it becomes clear, that maybe as patients, we have failed to own up to some of our responsibilities. Menstrual cycle disorders are uncomfortable to talk about. Who really wants to talk about never ending periods or blood clots—that’s just gross. And pain, one shouldn’t whine about menstrual pain, it’s unbecoming. Then there is the brain fog, fatigue, moodiness— all part of being a woman, or at least that’s what we’re led to believe. What if this isn’t normal? What if we, as women, are relegating our health prospects to ignorance? The Susan G. Komen Foundation did not come to prominence through silence, neither did the Endometriosis Foundation of America or any of the other women’s health organizations.

It is when we begin talking to each other and to our doctors that we can make it clear that these things are important; that the paucity of women’s health options is not acceptable. We need to become experts in our own health, to discern what’s normal and what’s not. We must drive the discourse, guide the research and build understanding for ourselves and our own well-being. We can’t wait for someone else to do this for us. Ignorance can be avoided.

See the full video clip with Dr. Mulley.

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