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Lucine Health Sciences and Hormones Matter are dedicated to improving healthcare with more research and better health and medication data.

Closed clinical trials data, positive publication bias and sometimes outright fraud, have made medical-decision making perilous and costly. According to the BMJ when published reports in peer-reviewed journals are re-analyzed to include the unpublished data for FDA-approved drugs, a whopping 93% of the outcomes changed.  Additional studies found that fully 50% of common therapeutic interventions are completely unproven. In women’s healthcare only 30% of Ob/Gyn Clinical Practice Guidelines are based on evidence, much of it biased. Worse yet, PNAS  reports that in 2012, that one in every 10,000 medical articles published was retracted, 67% of the retractions were due to misconduct with the vast majority (43%) for fraud or suspected fraud. We think that is unacceptable, and so should you.

Data matter. One cannot practice medicine, make personal healthcare decisions or business decisions without accurate data. We’re working to change that, one study at a time.

Health Data for the Real World

Want to know if a medication works, go to the patient. Want to know if a treatment has side-effects, go to the patient. We bring the patient back into the research equation with large, direct-to-patient medication and treatment research. We began with a series of women’s health studies and are expanding into general health, but central to each of our studies, is the belief that the patient is key.

Take a few minutes to complete a survey about health, hormones, medications and life in general. Take as many health surveys as are applicable and share this page with your friends. All surveys are anonymous and completely voluntary. Your data matter.

Health Surveys for Real Women

Real Risk Study: Birth Control and Blood Clots

Blood clots are a serious complication of hormonal contraceptive use and can be disabling or even fatal. Although some risk factors are already known, such as a family history of blood clots, increasing age, and smoking, many women who have suffered blood clots while on hormonal contraception have none of these risk factors. We believe that a deeper understanding of additional medical and lifestyle factors affecting a woman’s risk is needed. If you or a loved one have suffered from a blood clot while using hormonal contraception, participate in this study and help provide women with information they need about their personal level of risk with these medications.

Why I Use Oral Contraceptives Survey

Oral contraceptives (birth control pills) are prescribed for a myriad of reasons unrelated to pregnancy prevention. Sometimes they work; sometimes they don’t. Wouldn’t it be nice if we knew which brands of birth control pills worked for which conditions? Better yet, wouldn’t it great if we could avoid the pills that didn’t work, made a particular condition worse or had a higher than average side-effect profile? Take this survey and help us figure it out. Your data may save another woman’s life and health. Phase 1 of this study is complete and the results are currently being analyzed. Please stay tuned for the release of phase 2 of this study, and phase 1 results.

The Hysterectomy Survey

By the age of 60 one in three women will have had a hysterectomy. Hysterectomy is one of the most common surgical procedures for a range of women’s health conditions. For some conditions, hysterectomy works wonders. While for other conditions it is only nominally successful. The purpose of the hysterectomy survey is to learn more about why hysterectomy works for some women’s health conditions and not others. We’d also like to learn more about the long-term health affects of hysterectomy – does a woman who has had a hysterectomy have a higher or lower risk of other health conditions? Take this survey and help improve women’s health.

The Gardasil Cervarix Survey

Women and their physicians need more data about the side-effects of the HPV vaccines, Gardasil and Cervarix. There is a lack of data about who is at risk for adverse events and whether certain pre-existing conditions increase one’s risk for an adverse event. There is also a lack of data about the long-term health effects of these vaccines. The purpose of this survey is to fill that data void; to learn more about the risks for, and nature of, the adverse events associated with each of the HPV vaccines, Gardasil and Cervarix. Take this survey and help improve women’s health options.

The Lupron Side Effects Survey

Leuprolide, more commonly known as Lupron, is the GnRH agonist prescribed for endometriosis, uterine fibroids or cysts, undiagnosed pelvic pain, precocious puberty, during infertility treatments, and to treat some cancers. It induces a menopause like state stopping menstruation and ovulation. It’s widespread use for pain-related female reproductive disorders such as endometriosis or fibroids is not well supported, with very few studies indicating its efficacy in either reducing pain or diagnosing or treating endometriosis or other pelvic pain conditions. Conversely, reports of safety issues are mounting, especially within the patient communities. The Lupron Side Effects Survey was designed to determine the range, rate and severity of side-effects and adverse events associated with Lupron use in women. Phase 1 of this study is complete and the results are currently being analyzed. Please stay tuned for the release of phase 2 of this study, and phase 1 results.

The Fluoroquinolone Antibiotic Side Effects Survey

Patients and their physicians need more data about the side-effects of the fluoroquinolone antibiotics. The purpose of this survey is to fill that data void; to learn more about the risks for and nature of adverse events associated with each of the fluoroquinolone antibiotics, Cipro, Levaquin, Avelox and others. This will be the first of a series of studies on fluoroquinolone reactions. Anyone who have been given one of these medications, whether a reaction developed or not, and/or the parents or other family members of children too young or patients too incapacitated to take the survey for themselves, should take this survey.

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  1. I still have lots of abdominal pain after I have had a full hysterectomy, 2 separate surgeries. I had severe endometriosis that they found during my second surgery where they had to open up my full abdomen to remove the endometriosis. I was told that it had adhered to the wall of my abdomin but the doctors all said that it should be taken care of. I still have lots of abdominal pain and this has been a real eye opener for me. What tests should be done to find out if they got it all, I feel like they did not remove it all. If anyone has any suggestions please please let me know. Thank you

  2. I have been to 2 doctors , diagnosis hyper/hypo diagnosis,recently Hishimoto. My weight started 135lbs,now150lbs, labs sometimes 0.00 and 0.02 and back down 🙁 l also have multiple sclerosis. My endocrinologist,always says not to worry,orders labs every 6 weeks and adjust levothyroxine.This has been going on for 10 months. Is my doctor doing enough? The way I feel,I repeatedly tell him but Im wonder if there is more he can do for me 🙁 Thank YOU

    1. The MS symptoms may be related to low T3 levels, we have some research on the subject on this blog under thyroid and demyelination. Also consider joining a group called ThyroidChange – they are fantastic. They have a Facebook group and website.

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