Do Hormones Matter with Clinical Trials Research?I am repeatedly struck by the avoidable ignorance that surrounds this industry. Women’s hormones are considered a fringe science by many, despite the fact that hormones modulate all bodily functions and impact all aspects of pharmacokinetic and pharmacodymanic response, the key variables evaluated in clinical trials research. Repeatedly, we […]
Reproductive senescence, the period of time in a woman’s life marked by the slowing and eventual cessation of reproductive function, frequently coincides with an increased risk of a host of neurodegenerative disorders from memory impairment to dementia and Alzheimer’s disease. Researchers have long postulated that the loss of ovarian hormones were responsible; estradiol, in particular, […]
Electromagnetic hypersensitivity syndrome (EHS) has gained increasing attention over the last few years. The syndrome is marked by a variety of non-specific symptoms following both acute or chronic exposure to electromagnetic fields. EHS symptoms manifest broadly across multiple organs, but are especially troubling when affecting the central nervous system. Over the last year and after […]
I have been reading some of the fascinating posts by Angela Stanton PhD concerning her research in migraine headaches. I regard the substance of her discussions as somewhat like dots on a chart that need to be connected. I learned a great deal about the chemistry involved in migraine. One of her comments that involves […]
Over the last several months Dr. Lonsdale and I have been working on a book about thiamine deficiency and dysautonomia. Last week I wrote about the presumed connection between the Zika virus and microcephaly where I hinted at a thiamine connection. One might say, that I have thiamine on the brain and that would be […]
In many of my clients, chronic upper constipation and gastroesophageal reflux disease (GERD) are misdiagnosed as bacterial overgrowth. Unfortunately, they are often non-responsive to antimicrobial treatments. Yet, sometimes the issues are fixed within a few days of vitamin B1 repletion. This has shown me that often times, the small intestinal bacterial overgrowth (SIBO) is simply […]
Cyclic vomiting syndrome (CVS) is classified in the medical literature as a “functional” disorder, characterized by stereotypical episodes of intense vomiting separated by weeks to months of wellness. Although it can occur at any age, the most common age of presentation is between three and seven years. There is no gender prominence. The precise pathophysiology […]
Even though women being prescribed Lupron (leuprolide) have, understandably, no clue about its adverse thyroid effects, it is no secret that Lupron adversely affects the thyroid gland. (The same could be said for adverse effects from Lupron on many other organs and bodily systems, but the focus here will be on the thyroid.) For decades, […]