...also increase orexin. Drugs that block glutamate, via its NMDA receptor, decrease orexin. Common migraine medications block glutamate and thereby may also
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...neurons. Moreover, during movements, orexinergic neurons are particularly active and orexin release increases. The evidence suggests that the orexinergic system directly participates
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...from the hypothalamus, is called orexin or hypocretin. Orexin and hypocretin are the same molecule that was discovered simultaneously by two separate
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The Brain Needs Protein, Say What?
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...Think fever. The orexin/hypocretin neurons are very sensitive thermosensors. And to make things even more interesting, this system regulates our motivation to
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A Kindled Brain: Long Term Lexapro Use Reactions
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...orexin. They also say that stress causes orexin deficiency. These same articles, as well as Dr. Marrs’ work, suggests that these levels
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Molecular Mimicry and Autoimmune Disease
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...proteins that then initiated immune system attacks on the hypocretin/orexin neurons. The hypocretin/orexin neurons are responsible for regulating wakefulness and known to
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Beyond Calories In and Calories Out
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...is a relatively new discovery and not widely appreciated, but a set of neurons in the hypothalamus called the orexin or hypocretin
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Digging Deeper into Mitochondrial Dysfunction
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...loss of appetite too, mitochondrial diminishments – recall the orexin/hypocretin system. By whatever pathway, declining mitochondrial energy production arises when danger signals,
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