gardasil adverse reactions

A Light at the End of the Tunnel: Uncovering Thiamine Deficiency

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Early Health Issues: Enuresis, Long Term Antibiotics and Gardasil

My name is Eva, I am 24 years old, I am from Spain and I would like to share my story. Since I was born I have been a very healthy and active girl. The only thing to note is that I have always had frequent urination and nocturnal enuresis until I was 12 years old. At age 13, I began having frequent bouts of tonsillitis and with each episode, I was given a course of antibiotics. Eventually, I was taking antibiotics every three months along with ibuprofen continuously. At 15 years old, they gave me the human papilloma vaccine (HPV) – Gardasil.

After the vaccine, I began having fructose and sorbitol malabsorption problems and because of the frequency of antibiotics, I developed abdominal pains. I had a very pale color on my face and I was a little more tired than usual. I kept getting sore throats and at age16 they removed the nasopharyngeal tonsil /adenoids. In spite of all of this, I was living a normal life and continued to excel in school, receiving honors degree in high school.

At 18 years old, I had another course of antibiotics. This time for three months because the pus plates of my throat did not go away. I was exhausted. In the end, it was determined that I had a staphylococcus aureus resistant infection that was resistant to penicillin. I had an antibiogram, and of all the chances of antibiotics to which I was sensitive, the doctor chose levofloxacin. I was given levofloxacin for treatment of 14 days.

A few days after the treatment, in September 2012, I moved to another city to start my university studies (2 careers at a time). After a month, I got another sore throat that continued for three months. They put me on intravenous antibiotic. The doctor proposed to me to have an operation on my tonsils and I accepted. Just before the operation, I became sick again, and since they could not operate on me with an infection, he prescribed a round of amoxicillin with clavulanic acid plus levofloxacin. It had been five months since I had taken the first course of levofloxacin. This was in February 2013. After the operation, a month later, my knee and jaw began to hurt on the left side of my body. The traumatologist told me he had nothing. The dentist took my wisdom tooth, did a root canal and made dental fillings on that side, but my pain continued. I finished the course and that summer was very stressful for different reasons.

At the end of the summer, I went back to take an antibiotic for a tooth infection. A week before the beginning of the course, in September 2013, I started to feel very tired, and one night, in the middle of the street, I got dizzy and lost my sight and I had to go to the floor for a while before recovering. That’s where the nightmare began. I began to have multiple symptoms: tachycardia, nervousness, dizziness, stomach pains, intolerances, etc. At the end. I had an analysis and they gave me a diagnosis: Hashimoto’s thyroiditis. They started to treat it and at 4 months, when I was “stable” (in lab numbers), my left ankle started to hurt as if they were squeezing me with a chain. It was horrible and it started to go up to the knee, to the hip and shoulder and the pain in my mouth was worse. All on the symptoms were on my left side. The doctor said I had tendinitis, without more importance.

Over the next four months, I began to weaken. I had no strength, my legs were weak, and my mental exhaustion was increasing. I went through all kinds of doctors: rheumatologists, neurologists, internal medicine, traumatologists, and at the end, they concluded that I had fibromyalgia and chronic fatigue syndrome. That’s it. That is the best they could do and they offered no help.

Taking Matters into My Own Hands: The Fluorquinolone Connection

I began to read to realize that they are catch-all diagnoses, where they put people with multiple symptoms. Eventually, I found a doctor who began to treat the intestinal microbiota, to change my diet, reduce stress, etc. This was from 2014 to 2016. While it is true that I learned to manage crises so as not to live with pain 24 hours a day, I was stuck. I was still exhausted and had neuralgia on the left side of my body. So over these last two years I have tried other doctors, I have gone to neurologists specialized in amino acid biochemistry, but nobody knows why my health has declined so much. I have tried acupuncture, antioxidant therapy, etc. At the same time, I have not stopped reading, until I came to this wonderful blog two months ago, and suddenly EUREKA! Everything makes sense. Nobody had told me until now the dangers of fluoroquinolones. It is true that there are people who notice the problems of the antibiotic while taking it and have to leave it, it started a month later, but everything fits. My symptoms include:

  • Chronic fatigue which is very debilitating. I have been at home for 5 years, barely able to go out. I cannot study, work, or anything.
  • I have neuralgia / neuropathy ONLY on the LEFT SIDE of the body (no one gives meaning to this), from the head to the left toe.
  • Muscle weakness and rigidity
  • Tendinitis
  • Intolerance to histamine
  • Polyuria, urinary frequency
  • Sleep problems, sleep is not refreshing. I have epic dreaming disorder that does not let me rest. This problem of dreaming and getting up very tired has been a problem since since I was 16.
  • Problems with noise and light; I have to sleep with plugs and mask.
  • Alterations of the nervous system; I startle easily. I have a lot of intolerance to stress.
  • Problems with basic regulation of the body
  • Dizziness every time I get up when I’m sitting or lying down.
  • Recurrent pharyngitis / sinusitis / chest pain.
  • Hashimoto’s thyroiditis
  • Mental exhaustion
  • Weight loss.
  • Intestinal problems, intolerances, dysbiosis, infection by chronic GERD.
  • Swallowing problems. (The left side of my throat is more inflamed on the inside and it is hard for me to pass the food. It gets stuck).

Surely there are more symptoms, but I forget.

At the Root of My Symptoms: Severe Thiamine Deficiency

After reading the work of Dr. Lonsdale, I measured my transketolase and the result suggests quite a deficiency of thiamine: activation TPPE 25%. So I’ll see if trying this I can improve, until now I was lost and I saw the light at the end of the tunnel.

Questions for Dr. Lonsdale: Hello doctor, first of all thank you immensely for your dedication and work, thank you for your research and your book, you are helping a lot of people. I was lost until I found Hormones Matter and read it.  The activation of TPPE is at 24.98%. As I have read, this suggests quite a deficiency of thiamine. I’m going to look for a doctor who wants to help me treat my deficiency. I’ve read that you have to be careful with paradoxical reactions. But I have several questions that I would like you to answer if it is possible:

  1. The urinary frequency since I was born could have something to do with thiamine deficiency? Would this suggest some kind of genetic problem?
  2. Is supplementation with thiamine forever or only until the transketolase of 0? What is the time of supplementation with thiamine? When would I have to repeat the analysis of transketolase to see how it evolves?
  3. Could it be that levofloxacin has done me irreparable damage and I always had thiamine problems? Or can it be something genetic? – What is the suggested treatment?
  4. I have read about 50mg Allithiamine, with large doses of magnesium and a multivitamin, but how high should Allithiamine go – 200mg, 300mg?
  5. What do I do in the face of a paradoxical reaction? Do I stop the supplementation a few days and continue again, or to endure the reaction and continue? I want to give this information to the doctor who will treat me, in addition to his book.
  6. Does it make sense to have only neuralgia on the left side of the body? It is as if I had two bodies, the joints on the right side do not hurt, nor the nerves, only on the left side. I do not have anyone in the family with a similar background. My maternal grandfather was an alcoholic but he managed to quit. My maternal grandmother, 2 aunts and my mother have hypertension. And on my father’s side, my grandmother has always been tired from a young age, with pains and thyroid problems.

Thank you very much, Eva.

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Between Fear and Hope: Another Japanese Girl Injured After the HPV Vaccine

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HPV Vaccine Injury in Japan

Yuka was 13 years old when she received the first dose of Gardasil, the HPV vaccine. Prior to the vaccine she was healthy. Her mother describes her as slim, pale, and of average physical strength. She had dry skin and was sensitive to smell but no other ailments. She had never had influenza even when another family member had it. Yuka enjoys drawing pictures, playing music and spends most of her time indoors. She had all infant vaccinations under Japanese government program, but never had optional vaccines such as influenza. She had her first Gardasil shot in August 2012 on her left shoulder, the second shot October 2012 on her right shoulder, and the third shot February 2013 on her left shoulder again.

HPV Vaccine Symptom Chronology

August 2012: Yuka often complained shoulder stiffness. We laughed that she was playing the guitar too much, and I gave shoulder massage to her. She started to take a nap during day, but I thought that it was due to heat in summer.

December 2012: a large number of viral warts occurred on extremities. They were treated by a dermatologist with liquid nitrogen treatment and soon completely cured.

February 2013: Yuka had frostbite on the feet for the first time in her life. The winter was not particularly cold. It was completely cured in three weeks with an ointment and by keeping warm.

May 2013: Yuka had an accident and inured the right eye. She was a member of a Japanese archery club in school, and one day when she was walking with an arrow in her hand, the arrow accidentally hit a wall and it reacted toward her face. She could have stopped the arrow moving toward the face if she had enough grip strength, but unfortunately the arrow slipped through her gripped hand and hit her eye. She had stitches on the bulbar conjunctiva, and the injury was completely cured in one month. I later began to suspect that the injury might be caused by muscle weakness in her hand.

First Hospital Visit Post HPV Vaccine

Sometime in July, I noticed Yuka’s lymph node swelling on the left neck and trapezius muscle swelling on both shoulders, with the left side more swollen than the right. Yuka complained that the shoulders were a little aching. There were no redness or fever. We decided to seek a diagnosis and took her to the hospital.

July 2013: First visit to hospital for the swollen lymph node and shoulders. Her alkaline phosphatase (ALP) test came back very high at 446 IU/L.  Since she was growing and so the doctors did not pay much attention to this value. This value has been high throughout. Other lab tests included:  Ferritin (Fe) – 52.8 ng/mL, white blood cell count (WBC) – 4670 (she has never been measured for this value before, but her mother has a low value of about 4000), platelet count (PLC_ – 160,000 mcL, blood sugar – 70 mg/dL (about 3 hours after meal), C Reactive Protein (CRP) – 0, hemoglobin 14.5 g/dL, differential leukocyte count normal.

An MRI of her shoulder and neck with contrast agent was completed. The results showed that there was one swollen lymph node with a diameter of about 1.8 cm on the left neck, close to shoulder blade, and there were a large number of swollen lymph nodes with a diameter of about 5 mm on the neck. The trapezius muscle did not appear inflamed on the MRI so the cause of her shoulder pain remained unrecognized.

Second Visit to Hospital Post HPV Vaccine: Additional Tests

Echo test for the neck to the shoulder was negative, like the MRI. A second set of blood tests revealed:

  • WBC 3410
  • Fe 93
  • Blood sugar (2 hours after meal) 85
  • CPK 39
  • IgG 1658
  • Antinuclear antibody was normal.

She was diagnosed with Complex Regional Pain Syndrome, chronic fatigue syndrome, and fibromyalgia. Yuka was prescribed Myonal and Neurotropin and told to come back in one month. The swollen lymph nodes disappeared, but when we came back from a holiday, swelling in both shoulders increased, and symptoms such as fatigue, headache, double vision, light sensitivity, hip joint pain, knee pain, difficulty moving her hands, and muscle weakness in lower extremities occurred. Although she was diagnosed as fibromyalgia and since she did not have fever but had swollen lymph nodes, we suspected that she was reacting to a foreign body. Then we suspected that it might be due to the HPV vaccine.

Third Visit to Hospital Post HPV Vaccine 

September 2013: This visit was follow-up to the previous visit and further tests. Yuka had a head MRI and EEG. Both tests were normal. The additional blood tests showed continued low white blood cell counts, WBC 3700. She was tested for amylase, a marker of pancreatic function. The results were high at 146 U/L. Her blood sugar was 86 mg/dL (2 hours after meal). Her creatine kinase (CK) was 42 U/L and creatinine 0.40 mg/dL, low. Other values were normal.

A doctor suspected peripheral neuropathy due to the HPV vaccine. The doctor said that since there was no inflammation, the acute phase had passed, continuing daily activities would help rehabilitation, and she would recover.

Fourth Hospital Visit Post HPV Vaccine: Cerebellar Ataxia

September to October 2013. This visit was also follow-up to the previous visit and further tests.  By this point, Yuka had gained weight. She wanted to eat something sweet and salty. Her appetite increased. She also had fatigue and headaches, was experiencing difficulty walking. She could not maintain balance while standing with her feet together. I noticed that Yuka had ataxia. She also had swelling on her face.

She was diagnosed with cerebellar ataxia, but was told that she would recover since there was no inflammation and the acute phase has passed. She was also told that since the functional disorder was mild she would almost completely recover. However, I felt that the symptoms were gradually worsening.

Test results: There was no abnormality in electromyogram.  In the blood test, the values of WBC, CK, and creatinine decreased slightly, pyruvic acid was normal, metabolism of sugar, fat and protein was normal. She started fursultiamine supplement together with other vitamin Bs and magnesium. (These supplements were started after reading Dr. Lonsdale’s articles.)

Fifth Hospital Visit Post HPV Vaccine

October to November 2013. We went to the neurological department, Kagoshima University Hospital. This visit was due to her symptoms worsening. She needed to see a specialist of immunology and encephalitis.

We suspected immune-mediated encephalitis, and visited this hospital, which has a research institute. Around this time, this hospital was designated as one of hospitals for the treatment of HPV vaccine injured.

There were no abnormality in blood test and thyroid function (tested only FT4 and TSH), catecholamine 3F normal, vitamins normal (probably due to supplements), the values of WBC, CK and creatinine were still low, amylase 166, CMV-IgG 41, Head MRI normal, CBF (SPECT) normal.

The doctor was convinced by seeing swollen shoulders that the cause was HPV vaccine; although there was no significant decrease in blood flow in SPECT. Since there were reports about symptoms like a collagen disease due to an immunostimulation reaction caused by HPV vaccines, we were told that Yuka would have a steroid pulse therapy. She also had clear symptoms of cerebellar ataxia.

After one course of the steroid pulse treatment, symptoms due to cerebellar ataxia and headache disappeared, but there was no change in the shoulder. Immediately after the pulse treatment, she complained pain in the whole body and strong headache.

December 2013: Fatigue and swelling in the shoulders almost disappeared. Her WBC decreased to 2200. There was one onset of hyperventilation and visited ER in Kagoshima University Hospital and subjected to arterial blood gas test. The blood test results at the time of hyperventilation showed there were decreases in phosphorous (P), postassium (K), magnesium (Mg), and ferritin( Fe).

She also had some blood tests and the results were as follows: monocyte 11.8 H, neutrophil 41.8 L, and WBC – leukocyte 2870L. This was one month after the steroid pulse.

January 2014: Yuka began taking an iron supplement, (Fe 20, Ferritin 44). Her iron levels increased to (Fe 65, Ferritin 21.1) after taking the supplement. There was recovery for WBC to 4900 and her platelet count increased to 192,000. She continued to take fursultiamine (Shionogi & Co., Ltd., Verix, neo).

April 2014:  Her period stopped.

May 2014: As the symptoms seemed to subside, she stopped taking supplements.

June 2014: She became mentally unstable and irritable.  Her character has changed.  We wonder if her brain is affected to some extent.

September 2014: Yuka has started to have fatigue, and visited the hospital. There was decrease in WBC 3200 and PLT 130,000, and with the results of Fe 36 and Ferritin 48.9, she has started to take an iron supplement again. Thyroid function was normal (FT 41.1, TSH 1.6, TSH receptor antibody normal). She is also taking Chlorella, zinc, magnesium, and fursultiamine.

Since the beginning of August, Yuka is taking Kamishoyosan-based Chinese medicine called, whose efficacy includes premenstrual syndrome, dysmenorrhea, irregular menstruation, menopausal syndrome, chronic hepatitis, liver cirrhosis(early stage), chronic gastritis, irritable bowel syndrome, anxiety disorder, insomnia, hand and finger dermatitis, etc.

Around July 2014, her nails started to show white raised vertical lines.  We worried that she might be lack of zinc, and she started to east oysters a lot, but from August Yuka asked to have zinc supplements instead of eating oysters.  We thought the loss of period might be due to zinc deficiency and Yuka was also worrying about hair loss possibility.  We wonder, which is better for zinc deficiency eating oysters or taking supplements?

Most Recent Blood Work Post HPV Vaccine

September 2014:
  • TSH receptor antibody （－） binding inhibition rate 3.8%, 
  • Thyroid test　(Thyroglobulin antibody by passive agglutination) LT100
  • Microsomal test (Anti thyroid microsomal antibody) LT100
  • Anti-TG antibody LT 10.0
  • TPOAB LT5.0
  • Thyroid globulin 6.7
  • TSH 1.6
  • FT4 1.1

One Year Post HPV Vaccine

Last summer when Yuka first became ill, she was suspected to have the Kikuchi disease.  After most of her symptoms had disappeared around early this year, her health started to deteriorate again this spring, and this time the symptoms like those of the Kikuchi disease seemed to reappear.

There have been two cases of the Kikuchi disease after HPV vaccine in Japan, and one of which has been reported in the literature.

Yuka has a sister (15 years old), who also had Gardasil at the same time.  She also had swelling and hypesthesia on the right face around the same time as Yuka had. Yuka’s sister loves sports and plays tennis outdoor, and is suntanned through the year. She had a severe acne, and was taking an antibiotics (several of two week courses) and Vitamin Bs when she had Gardasil. Yuka’s sister did not have any further symptoms due to Gardasil.  We wonder if the antibiotics helped or Vitamin Bs helped Yuka’s sister or maybe even the Vitamin D formed by being outdoors. Both of the girls still have swelling on their faces, but no hypesthesia (diminished capacity for sensation).

Postscript: This article was written originally in Japanese by Yuka’s mom and translated to English by Madoka Hazuki.

Participate in Research

Hormones MatterTM is conducting research on the side effects and adverse events associated with Gardasil and its counterpart Cervarix. If you or your daughter has had either HPV vaccine, please take this important survey. The Gardasil Cervarix HPV Vaccine Survey.

Hormones MatterTM conducts other crowdsourced surveys on medication reactions. To take one of our other surveys, click here.

To sign up for our newsletter and receive weekly updates on the latest research news, click here.

What Else Can I Do To Help?

Hormones MatterTM is completely unfunded at this juncture and we rely entirely on crowdsourcing and volunteers to conduct the research and produce quality health education materials for the public. If you’d like help us improve healthcare with better data, get involved. Become an advocate, spread the word about our site, our research and our mission. Suggest a study. Share a study. Join our team. Write for us. Partner with us. Help us grow. For more information contact us at: info@hormonesmatter.com.

To support Hormones Matter and our research projects – Crowdfund Us.

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Walking on the Edge of a Sword: Cervarix Injury in Japan

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cervarix

This is the story of my teenage daughter who, beginning in 2010, received a series of vaccinations that culminated with the three shot HPV vaccine, Cervarix (Gardasil in the US). Although she had some health issues as an infant and child, she was thriving and doing well prior to the vaccine. After the Cervarix vaccine series this all changed.

Sharne was born in 1998. Her health issues pre-vaccine included: pervasive developmental disorder (PDD), a form of Aspergers, infantile asthma, atopic dermatitis, pyelitis, otitis media, Candida, hemolytic streptococcus, pneumonia, wart, FMF (periodic fever syndrome), agrochemical sensitivity and repeated stomatitis. Her immunization history was as follows:

  • 15 May 2010 DT BIKEN (Lot. No. 2E007 2011.6.8, 0.1ml) left arm
  • 19 March 2011 Japanese encephalitis BIKEN (JR059 2012.5.18, 0.5ml) left arm
  • 25 June 2011 Measles and Rubella Takeda (Lot. No. Y116 2012.2.24, 0.5ml) left arm
  • 27 July 2011 HPV  Cervarix  1st shot (Lot. No. AHPVA129CA, 0.5ml) left arm
  • 17 October 2011  Cervarix  2nd shot (Lot. No. AHPVA143AA, 0.5ml) right arm
  • 26 March 2012  Cervarix  3rd shot (Lot. No. AHPVA161BA 0.5ml) left arm

Before the Cervarix Vaccine

Sharne was born October 02, 1998. Prior to Cervarix vaccine, she enjoyed her school life. She liked to be in the school rather than being home, including going to an evening school for extra study.  As she wanted to gain accreditation to a high school, she tried to go to school even when she had a fever of 40 degree centigrade because in order to get the accreditation she was allowed to be absent from school only up to 5 days

Prior to the HPV vaccine, Sharne did not need to sleep for a long time, and she woke up early even when she went to bed late the day before. Before the symptoms occurred, she used to wake up at five o’clock in the morning. She’d read her favorite books, and then went to run around the house for about 10 minutes.

She was an athlete and was the fastest 1000 meter runner in her class when she was in 7th grade. She had strong lungs, and her respiration rate and pulse rate had been low since she was a little girl, but it is now is much higher. Her pulse is averages 70-80 beats per minute; average for some, but several points higher for her.

She used to prepare breakfast by herself, do homework and go to school. She was really independent, managed her own schedule, found whatever she wanted to do, and when she needed to be taken to or picked up she just told me the time to be taken to or picked up.  She never conflicted with others, avoided any dispute, and was a very quiet, gentle and good natured child.

After the Cervarix Vaccine

Now she cannot do what she could do previously. She has difficulties remembering things. She cannot remember what she has done. She cannot manage her own things, stationary, notebooks, glasses.  She used to look after her things very carefully, and never asked where they were. She’d never forgotten what she needed to take to school, but now she leaves her glasses on the floor of her bedroom or in a washing bowl even for two weeks. She cries when she cannot find her notebook, and she cannot remember what she did in the past.

Her IQ and test scores have dropped a lot and continue to drop.

She says impolite things to teachers or family members and becomes violent like an insane person. She hates most of people around her.

Recently, she cannot understand what she is going to do or where she is. In addition, she has muscle weakness in legs, and cannot raise her left foot. Her grip strength dropped from about 30 kgf to 5 or 6 kgf.

The Progression of Symptoms Post – HPV Vaccine

Looking back now, it seemed to have started after the first Cervarix shot, but it gradually worsened for about two weeks after the third shot, and half a year later she could not get up at all. Symptoms:

  • After 1st shot: asthma attack (the first time for seven years).
  • After 2nd shot: malaise, long-lasting urticaria, repeated nosebleed
  • After 3rd shot: in MRI, extension of T2, cerebral blood flow decrease, atrial rhythm, arrhythmia, increase of eosinophil, IgE, IgD, and complement titer, abnormal malaise, chronic slight fever, clouding of consciousness, hypersomnia, brain function deterioration such as memory, comprehension, calculation, and execution functions, personality change, irritability, aggression, depression, childishness, behaving like a baby, hyperpnea, respiratory distress, muscle weakness, back pain, headache, parotitis, temporomandibular arthritis, dysphagia, stomatitis, abdominal pain, vomiting, diarrhea, back pain, muscle pain, abnormal vision, photophobia, double vision, reduced vision, etc.

Timeline of Symptoms Post Cervarix Shots

2012

April: about 2 weeks after the third shot (March 26), exertional hyperpnoea and muscle weakness occurred.

May or June: started experiencing malaise, gastrointestinal symptoms such as vomiting, headache, chest pain, and anginal symptoms during nocturnal rest. There was muscle weakness when getting off from her bicycle in the school and could not stand up.

September: could not get up, altered state of consciousness lasted for a long time, there were anginal symptoms, atrial rhythm, arrhythmia, blood flow decrease, extension of T2 in MRI, and leukoaraiosis.

October to December: treated with steroid. Although malaise had dramatically improved, brain blood flow did not improve, accumulation was observed in the hippocampus, and the treatment was stopped.

 2013

January: malaise worsened seriously. There were depression, suicidal thought, and personality change (irritability, excitability, persecutory delusion).  Even in school she cried loudly like a one-year old baby and dashed out from the classroom.

June: we noticed the association with the vaccine when watching a TV news about suspension of recommendation of HPV vaccine.  Around this time, she became violent at night. Cried loudly like roaring. Sharne threw her younger brother by the full force. (This violence disappeared soon after IVIG.)

August: we saw Dr. Sasaki, and he proposed three treatments, that included, steroid pulse, IVIG, and an immunosuppressive agent.

September: immunoglobulin (due to fever, discontinued on the 3rd day, she became cheerful on the 2nd day, and the sensation of toes returned. Malaise also improved a little.  Blood flow increased, and the best results for SPECT so far), but involuntary movement gradually intensified.

2014

February: steroid pulse (after about 2 weeks, headache and back ache, etc. decreased, cognitive function and facial expression a improved slightly, the time of sleep during day decreased, but after about 20 days new systemic joint pain and excruciating pain started, and malaise, gastrointestinal symptoms, etc. also restarted.)

Her sensitivity to glare and the double vision disappeared.  Involuntary movement started to appear.

March: 2nd cycle of steroid pulse (this time, there were no effects on mental strength and malaise, and there was a symptom like muscle weakness, which had appeared with the altered state of consciousness in the autumn 2012), involuntary movement and muscle weakness seemed to increase, and IgG decreased.

May: she was depressed. She received immunoadsorption therapy, involuntary movement decreased, but spasm and tremor have started. Mental motivation improved, and gentle character has returned. Malaise has alleviated, and daily life became almost normal.

June: malaise returned in one week after discharge from the hospital, and IgG decreased.

July: motivation dropped. Mental symptoms have started.

Lab Tests and Other Diagnostic Results

  • Cerebrospinal fluid test results: autumn 2013: contaminated with blood, but IgG was as high as 5.8 (this is not influenced by serum contamination)
  • February 2014: cell count 12, CD4 64.9, CD8 31.4, cytotoxic T cell, granzyme B 1.3
  • Diagnosed as a possibility of subacute encephalitis.
  • April 2014: abnormal values for various types of interleukins, etc.
  • June 2014: antiganglioside antibody positive

The Lesson I Learned too late

‘We need question even what the government is doing.’ This is what I learned with this huge and irreparable mistake. I tell our story because I do not want to other parents to make the same mistake and because we need help understanding the post-vaccine reactions, so that our children, already injured by the Cervarix vaccine can recover.

Vaccination of boys has already started in some countries, and clinical trials have begun in Japan. In order to protect the future of children, please think and research before you vaccinate. I will let my voice be heard in order for many people to receive information about the dangers of the HPV vaccine.

Cervarix Adverse Effects in Japan

There are more than 2000 reports about adverse effects in Japan, but some doctors refuse to report. There have been more than 1000 contacts to the network of HPVW injured people in Japan, the number of people registered exceeds 255, but still there are only a few medical institutions that care for injured.  The government should support and subsidize medical institutions that exert themselves for elucidation of the mechanisms of the cause and establishment of the way to treat underlying causes.

Postscript: This article was written originally in Japanese and translated to English by a friend of Hormones Matter.

Participate in Research

Hormones MatterTM is conducting research on the side effects and adverse events associated with Gardasil and its counterpart Cervarix. If you or your daughter has had either HPV vaccine, please take this important survey. The Gardasil Cervarix HPV Vaccine Survey.

Hormones MatterTM conducts other crowdsourced surveys on medication reactions. To take one of our other surveys, click here.

To sign up for our newsletter and receive weekly updates on the latest research news, click here.

What Else Can I Do To Help?

Hormones MatterTM is completely unfunded at this juncture and we rely entirely on crowdsourcing and volunteers to conduct the research and produce quality health education materials for the public. If you’d like help us improve healthcare with better data, get involved. Become an advocate, spread the word about our site, our research and our mission. Suggest a study. Share a study. Join our team. Write for us. Partner with us. Help us grow. For more information contact us at: info@hormonesmatter.com.

To support Hormones Matter and our research projects – Crowdfund Us.

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My Son’s Gardasil Story and Thiamine Deficiency

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On June 16th 2012 my son complained of ear pain, so I took him to his doctor thinking he had an ear infection. He had no infection but his doctor suggested doing a physical exam since he had not been in for a couple of years. My son had just turned 18 years old three weeks prior and just graduated from high school. He was happy, healthy, and active. After the exam I was called into the room. His doctor said he was in good health and observed no problems, but since he would be going off to college in the fall, he recommended that he should receive the meningococcal vaccine along with the Gardasil vaccine. In his words, “HPV is rampant in colleges and he should have this vaccine.” This had been my son’s physician since birth, and having no prior knowledge of the Gardasil vaccine controversy, I trusted him and agreed to these two vaccines that day.

There was absolutely no discussion of possible harmful side effects.

My son did not have any immediate reactions that I can remember, but on July 30th 2012 that all changed. We were out to lunch and when his food arrived he looked at me with a very strange look on his face and said that he just didn’t feel right, something was wrong. He could not eat that day even though he was hungry just prior. He would complain of severe stomach pain that came and went over the next few weeks.

On August 7th 2012 he received the second dose of Gardasil. His stomach pain increased in severity, but we still did not make the Gardasil connection. Who would think that a vaccine for HPV would cause stomach aches?

Just nine days after that second injection, he felt he needed to go in and see his doctor. The pain was becoming unbearable. The doctor prescribed antacids but this only made his problem worse, so he then suggested an endoscopy. The endoscopy came back completely normal. At this point his doctor felt that his stomach pain was due to stress and anxiety because he was going off to college. The doctor suggested that he should “go talk to someone.” I knew for a fact that the pain was not in his head or simply due to stress. It was real. Now, almost a year later, and with the knowledge of the possible side effects of the Gardasil vaccine, I am very angry that his doctor did not recognize “severe stomach aches” as being one of the Gardasil side effects. How did he not connect those dots, especially given the fact that my son was in his office just nine days after receiving the second dose complaining of that very thing? This recognition would have prevented him from getting that dreadful final dose.

My son left for college and soon after began developing other symptoms, mainly extreme fatigue and brain fog. He made it through the quarter and came home for Winter break. On December 27th he received the 3rd and final dose of Gardasil. The very next evening he became extremely sick. All the symptoms he had been experiencing along with many others became instantly worse. I was finally able to make the Gardasil connection. Since then he has had more symptoms than I can list, sinus headaches, pain at the base of his skull, fever, chills, hair loss, vision changes, gallbladder pain/gallstones, sleep disturbances, tingling, numbness, no appetite, weight loss, anxiety, excessive thirst, salt cravings, kidney issues, liver issues, heart palpitations, slow heartbeat, fast heartbeat, dizzy, rashes, mouth sores, yeast issues, low stomach acid… the list goes on. To this day he still suffers from many of these symptoms.

What has followed are many doctors and  many, many tests; most of which have come back normal with the exception of his most recent test. After reading Dr. Lonsdale’s article on thiamine deficiency and his recommendation for Gardasil injured to have a red cell transketolase blood test,  I immediately requested one for my son. I researched the symptoms of thiamine deficiency and he pretty much had every single one. The test came back strongly positive. He was severely thiamine deficient.

This is where we are today. We started immediate supplementation with oral alliathiamine and we are looking into possible IV supplementation, for perhaps, a quicker, more thorough improvement. I sincerely hope that this discovery might be the key to my son finally being well again and that this devastating nightmare may finally come to an end.

Participate in Research

Hormones MatterTM is conducting research on the side effects and adverse events associated with Gardasil and its counterpart Cervarix. If you or your daughter has had either HPV vaccine (we hope to launch the male version soon), please take this important survey. The Gardasil Cervarix HPV Vaccine Survey.

To take one of our other Real Women. Real Data.TM surveys, click here.

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Rolling the Dice with the HPV Vaccine

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If you are the parent of a minor child, you most likely have heard about one or both of the HPV (human papillomavirus) vaccines currently on the market. A trip to the pediatrician’s office with a teen or pre-teen is typically where the first discussion takes place. The doctor will dutifully recite information. HPV is the most common sexually transmitted virus in the United States. As a parent, that gets your attention. They go on to further state that the vaccine will protect your child from the strains of the virus that most commonly cause cervical cancer in females and genital warts in males. These are both very uncomfortable subjects for most of us. However, as parents, we want to protect our children at all costs from anything and everything possible.

As with any vaccine, the parent is provided a pamphlet or sheet containing the standard information: what is HPV, why get vaccinated, who should get vaccinated, and the obligatory safety information. After reading the information and listening to the doctor’s recommendation explaining that the vaccine is very safe (and it seems to be for most patients), many parents make the decision to have their child protected. I was one of them. I rolled the dice and sadly, my daughter lost.

The information pamphlet states that the vaccine has been used in the United States for about six years and has been very safe. You are warned about pain and swelling of the injection site, fever, headache, and the most troublesome side effect, fainting. The patient is required to remain in the doctor’s office for a period of time after the injection as a safety precaution.

What the information pamphlet does not address is that over 29,300 injuries and 136 deaths have been reported following HPV vaccines. Vaccine injury reporting is voluntary in our country and the Center for Disease Control acknowledges that adverse events, as they are called, may be 10 to 100 times greater than those actually reported. Do the math.  The reported numbers seem very significant to me, but I am the mother of one of the injured. I trust we can all agree that the actual numbers could be staggering.

The list of new medical conditions being reported following the HPV vaccine is also staggering, I counted 144 conditions. My daughter has 31 of them. She suffers mainly from neurological, autoimmune, and adrenal issues. The worst offender is a migraine-like headache that has been present every day, all day and night for more than a year. The neurologist refers to it as migraine-like because all the symptoms are there yet it does not respond to any medication. Her immune system has also been compromised. She suffers from leaky gut syndrome and now has sensitivity to 20 common foods. Dealing with this for more than a year now has taken a toll on her 16-year-old body. Chronic pain has lead to depression and adrenal fatigue. All of this in a girl who had what was described as an “unremarkable’ medical history prior to vaccination.

While my daughter’s symptoms are grave, she really is one of the lucky ones.  Many of the injured suffer from daily seizures or even multiple seizures per day.  My daughter does not. For that, I am thankful every day. Having a child in crisis is hard. Having a child with a medical crisis that medical doctors do not know how to reverse is even more difficult. My decision to protect her, in fact, caused her great harm.

Choosing to give your child a vaccination is a personal decision, but it is one that should not be taken lightly. Do your own research, do not simply rely on the information pamphlet, it is, after all, written by the vaccine manufacturer. I learned this lesson the hard way.  When you decide if you will roll the dice, please, for the sake of your child, remember this:  Education conquers fear and knowledge is power.

Gardasil Cervarix HPV Vaccine Research

Hormones MatterTM is conducting a large scale assessment of symptoms and adverse reactions associated with the HPV vaccines, Gardasil and Cervarix. If you, your daughter, other family member or friend have had either of these vaccines, we encourage you to take this important survey. The data collected with help delineate the range, severity, frequency and onset of health symptoms associated with Gardasil and/or Cervarix. For more information or to take the survey: The Gardasil Cervarix HPV Vaccine Survey.

 

 

 

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One Less After Gardasil

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Imagine for a moment having an outgoing, vibrant daughter, just turned 21 years old – her whole life ahead of her. She’s a bright, outgoing, athletic, college student, kind and compassionate. She has hopes and dreams just waiting to be fulfilled. No parent could ask for more. All parental bias aside, this was our daughter, Brittney, before Gardasil.

When Brittney received her first Gardasil injection in June of 2007, she was told that the only real risk involved was the possibility of her having a small seizure shortly after the shot was administered. She did not react within the 15-minute window, during which the medical staff monitored her. She thought she had nothing to worry about. She admitted later, after she took the first dose, that the doctor had told her she could get the HPV viruses that cause cervical cancer through a lab accident at college, (where her blood might mingle with someone infected). She had been in a lab accident just a few months previous, so the fear of being infected was immense.

When she passed out the next morning on our family room floor, she got up wondering what had happened. Britt chalked it up to the possibility of being dehydrated. She had been quite active for several months. Several years before she had fainted from dehydration, so she didn’t think much of it. She was so unconcerned she didn’t even mention the incident until over a week later. By this point, she had experienced two other unusual episodes.

The next incident occurred nine days after her HPV vaccine injection. She had what we now know was a partial seizure. Three days later, her legs gave out while she was at a water park. Hammering pain spread up and down her legs for 15 minutes, then disappeared. As a parent, I was beginning to think the incidents were related, but was not sure how they were connected.

Britt is a fighter. She never backed down from anything, but charged head-on until she accomplished her goals. The nagging leg pain and the strange episodes of blacking out were just one more challenge to conquer. She pushed through summer determined nothing would prevent her from achieving her goal to graduate college and pursue a dream of becoming a singer/dancer.

Sometime mid-July, our doctor reassured us that what Brittney was experiencing had nothing to do with Gardasil. We were relieved – at least we could relax on that score…

In July, we took Britt to Myrtle Beach for a belated 21st birthday celebration. During this week, Brittney began to lose control of her emotions off and on. She would be completely normal, then suddenly explode. She would scream at us that we were trying to upset her, or prevent her from living her life. She had never acted this way in her life. Both my husband and I were shocked at her unprovoked outbursts. We spent the entire vacation walking on eggshells when she was present. It seemed the most innocent remark could set her off. The only thing that seemed to soothe her during that week was going to the ocean and walking the beaches.

In August, she had another ‘episode’ as the doctor called them, this time in the company of several college chums. One of them had a sister who experienced many seizures while growing up. She told Britt’s boyfriend at the time that it looked like Britt was having a partial seizure.

Unfortunately, the boyfriend would not accept this reality and shoved an inhaler in her mouth while she was unconscious and depressed it. Britt came around, choking on the aerosol. She told me about the incident later, which was upsetting. She also mentioned the incident to her doctor, but nothing more than a blood test was taken. The results showed that she was a little low on Potassium so she was told to eat more bananas.

In late August 2007, Britt received her second injection of Gardasil – again with no reaction during the 15 minutes of post-vaccination observation. But, within a week she began to have nagging issues with head pressure, like a cap with too tight of a band around her head. Over the next couple of weeks this progressed to the point where she could barely open her mouth because the muscles in her jaw were so tight. She began falling down for no reason. After three weeks, she began to experience blurred, doubled vision. She was extremely sensitive to light of any type. The pressure in her head was so intense, she was passing out daily. She developed a swelling that appeared to be filled with fluid at the base of her skull and along her spine. Along with all of the other symptoms, severe pain was raging through her body. As soon as her doctor examined the swelling, Britt was sent straight to the hospital.

Multiple tests were done, but nothing showed up on any of them. Britt was sent home with a couple of pain tablets. The resident on call felt she had some sort of brain virus and that it would go away in a couple of days.

From this point on, Brittney’s health deteriorated quickly. She couldn’t read anymore because the words seemed to run together or off the pages. She could no longer tolerate light or sound of any kind. We had to speak in whispers when near her or go up to the third floor and speak very softly. Her hearing was so sensitive that she could hear sirens more than three to four miles away and conversations several rooms away. She couldn’t sit in the same room with a television or radio on. Her pain was so bad, she cried all of the time. We bought noise cancelling headphones so she could tolerate trips to the doctor’s office. She had to have wrap around dark glasses – regular sunglasses were not sufficient to protect her from the severe sensitivity to light.

The nightmare didn’t stop there. Her face would sometimes droop to one side like it was sliding off her skull as pressure in her head grew worse. Seizures and stroking migraines began to happen 24/7. Her stomach was upset all the time. She could hardly keep anything down. She lost sensation in her legs and fingertips, she became completely bedridden, and simply longed to die.

Over the next three years, Britt was seen by over 60 doctors, including teams at Johns Hopkins Hospital, the Cleveland Clinic and the University Of Cincinnati Hospital. None of them could help her. She was so sick to her stomach, she could eat nothing but three ounces of protein drink at a time, fed with a baby spoon. Not one doctor suggested we have her stomach looked at. They simply dismissed it as being stressed, over-reacting to life, or a conversion disorder.

Just to give you an idea of what her new life is like, I will briefly touch on a few events:

  • January to March 2008 – Britt was totally bedridden and seemed to be wasting away. She nearly died before we found a doctor who helped alleviate some of her more severe issues. Unfortunately, she became intolerant of the medications that helped her. She began reacting to everything the doctor gave her. She was sent to many specialists who threw up their hands in frustration at her body’s resistance to treatments.
  • Early 2009 – We found an alternative chiropractor who recommended Okra Pepsin3 with Multizyme to help settle the lining of Britt’s gastro-intestinal tract. After several months, Britt was able to eat many organic and natural foods for the first time since her second Gardasil injection.
  • June 2009 – Brittney seemed to improve for a couple of months, including strength, but this didn’t last. By December she had lost all feeling in her legs, plus the head pressure had returned more intensely.
  • January 2010 – After being seen at Johns Hopkins Hospital Britt’s legs were put into massage bladders. This seemed to relieve some of the loss of feeling – when she left she could feel her upper thighs again. By spring, she was working with a researcher who was willing to try to help with some of Britt’s other issues. He suggested CoQ10, vitamin K Complex, magnesium, calcium and Vitamin D3 supplements. Britt’s sensitivity to light and sound diminished and some of her pain was alleviated. She had a boost of energy for the first time in three years.
  • April 2010 – A migraine specialist administered pain blocks to the back of her head (scalp) which relieved a great deal of the head pressure, jaw pain and complex migraines. She began to eat better.
  • June 2010 to January 2011 – Brittney seemed to be doing well. An alternative doctor had made some modifications to her diet that seemed to mitigate some of her more severe symptoms. She began a gluten-free, casein-free, sugar-free diet, avoiding Citric Acid, MSG, artificial preservatives, and mushrooms.
  • January 2011 – She was exposed to a virus. Her immune system could not handle it. She physically collapsed. The doctor told us that her immune system was crashing and he couldn’t help her. Britt’s grandmother sent over what we thought was homemade chicken with dumplings to boost her health. Brittney gained 60 pounds during the following 24 – 30 hours. We discovered there was Citric Acid in the broth. Nothing would bring the swelling down but time.
  • May to June 2011 – Her more severe pain symptoms calmed down a bit, but she was still vomiting. Her abdomen and stomach swelled to the point where she looked like she was six months pregnant.
  • 2011 – We finally found a gastroenterologist who was willing to examine Britt’s stomach. She was horrified at what she found – Gastroparesis – a damaged Vagus nerve in Britt’s stomach which prevented normal digestion and emptying of her stomach.

Last summer, 2012, we started taking Britt to another alternative doctor. Gradually Britt began to have a small semblance of the life she had before Gardasil. After months of IV treatments, she has been able to handle a large crowd at a cinema, a very busy restaurant, and even go to the mall briefly. Understand that these events have taken place weeks apart. She still has a long way to go. She has been able to enjoy her favorite music with the speakers “normal” without suffering. She wears her wrap-around low vision glasses only on very bad days. She is able to walk on her own for short distances despite the lack of feeling in her legs.

January to April 2013 – Britt has had a huge setback which we believe was triggered by an LH hormone test. This test was to check the levels of these brain-based hormones to try to regulate them. She felt like the Gardasil nightmare was starting all over again before the hormone was neutralized. Within days of the test she began a slow increase of seizure activity, which built from a couple over a four month period, to multiple, daily events. Some were so severe that her power port shifted under her skin. After four weeks of non-stop seizures, we were able to get her in to the doctor’s office for a much needed IV. It took her nurse three tries to find, then flush the port, before the IV therapy could begin. Her seizure activity has now slowed to a minimum. As long as she stays on track for the IV’s, (basic vitamin/mineral infusions that help boost her immune system, calm physical issues, improve mal-absorption of nutrients), she can maintain much of her homebound activities. There are still periods when we talk with her that she displays signs of confusion, memory loss, and inability to concentrate.

Brittney has been ruled “Disabled” due to residuals of Gardasil by the SSA. She receives some compensation through the SSI which is helping pay her myriad medical bills.

Nearly six years ago, Gardasil changed our lives forever. It has been a nightmare without end watching our daughter suffer through every stage of the past several years. She has literally become ONE LESS!

 

Hormones MatterTM is conducting research on the side effects and adverse events associated with Gardasil and its counterpart Cervarix. If you or your daughter has had either HPV vaccine, please take this important survey. The Gardasil Cervarix HPV Vaccine Survey. 

To take one of our other Real Women. Real Data.TM surveys, click here.

To sign up for our newsletter and receive weekly updates on the latest research news, click here.

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