vaccine reactions

Covid Notes: Vertigo and Guillain-Barre After Vaccination

7572 views

My husband developed severe vertigo after the second dose of the Pfizer vaccine. Vertigo is a disabling condition marked by a sensation of spinning and disequilibrium that is believed to be caused by inner ear, eye, and/or cervicogenic disruptions. Vertigo has an estimated incidence rate of 64 per 100,000 per year or about 2.4% across a lifetime. The incidence rate of post-vaccine vertigo for the Pfizer vaccine is approximately .8%. Assuming that most of the reactions occur with the second dose, with over 281 million doses (140 million second doses) given in the US when he developed vertigo, we get at least 1.1 million cases of vaccine-induced vertigo. That is 1,100 cases per 100,000 – well above the average incidence rate. In as much as reporting to VAERS, the vaccine adverse events database is voluntary and is said to represent a mere 1-10% of total cases, the numbers could be much higher.

A work colleague of his developed Guillian-Barre Syndrome (GBS) around the same time. GBS is an autoimmune condition attacking peripheral nerve myelination, causing weakness and paralysis. This was also after the Pfizer vaccine. The rate of post-Pfizer/COVID vaccine GBS is ambiguous. One study estimated the rate of GBS after COVID vaccination to be anywhere from 1 case per million to 53 cases per million. Another study calculated the rate to be 20.5 per 100,000 person-years. Person years is a funky calculation that allows estimates of incidence in groups of people across time. Despite the confusing nature of the calculation, what these results tell us, is that with the COVID vaccines the incidence of GBS has escalated and is a least 10-20X higher than it was previously and given the scale of the vaccination program, we’re likely to see exponentially more cases than ever before.

Medication and Vaccine Induced Vertigo and GBS

medication induced vertigo
Figure 1. Medication induced vertigo.

Prior to the COVID vaccines, both conditions had been attributed to an array of precipitating factors including viral infection, vaccines, and medication adverse reactions. The list of medications and vaccines capable of causing either vertigo or GBS is long, so long that it is difficult not to wonder if pharmaceuticals underlie the majority of cases for both of these disease processes. Figure 1. details some of the medications capable of inducing vertigo. A more extensive list can be found here.

A study in 1996 found GBS induced after a variety vaccines including: influenza, tetanus, hepatitis B, rabies, oral polio, measles, mumps, and rubella, and the haemophilus influenzae B conjugate vaccines. Medications that were recognized as causing GBS at the time included: streptokinase, corticosteroids, danazol, captopril, d-penicillamine, oxytocin, and cantharidin. Medscape lists vaccines and fluoroquinolones as possible culprits, but here again, the research is equivocal.

Regardless, neither condition is considered together or as having any common mechanisms. Frankly, until recently, I believed they were separate disease processes altogether. Now, I am not so sure. They may be different manifestations of the same or a similar process: nerve demyelination triggered by mitochondrial depletion in the affected area.

Why do I think they might be similar? When we consider how many fundamentally different formulations of pharmaceutical chemicals initiate one or both of these reactions, it suggests that these reactions are not simply an outgrowth of the chemical’s mechanisms of action. It also suggests that these reactions are not likely to be simply off-target effects that were somehow either missed or undisclosed by the manufacturers. Rather, I suspect these reactions go deeper, to some ‘final’ common pathway that all drugs, vaccines, or really for that matter, severe stressors elicit. It’s not that these drugs are not culpable, they are, just not in the manner we are accustomed to believing.

We are used to viewing drug reactions relative to the drug’s specific mechanisms of action. That is, the drug blocks or upregulates this or that receptor or channel and so we believe that adverse reactions and/or the illnesses initiated develop directly in relation to those actions. Sometimes reactions develop beyond the mechanisms for which the drug was purposed. These are considered ‘off-target’ effects. Off-target effects imply that the drug’s actions affect the functioning of systems beyond what they were designed for. As an example, let’s say a drug was designed to regulate calcium (CA2+) channels in the heart in order to control blood pressure. Off-target reactions would be those that involve Ca2+ channels elsewhere in the body. In reality, since all bodily systems are conserved and thus repeated in all tissue, there is no such thing as an off-target effect. These effects are simply drug effects. Labeling these effects ‘off-target’ is nothing more than a sleight-of-hand meant to distract us from discernment, but I digress.

For vaccine reactions, much of the adverse reaction research focuses on the potential toxicity of the ingredients used to carry/deliver, maximize and/or preserve the viral components. Called adjuvants or excipients, these extra ingredients are often toxic to varying degrees, but they boost immune response (because that’s what happens when the body recognizes toxins) so that is why they are included. As one might expect, these products contain a long list of adjuvants, any one of them is capable of evoking illness under any circumstances, but especially when the individual into whom they are put, has underlying health issues.

The mRNA vaccines are a little different. While they have noticeably fewer ‘ingredients’ than traditional vaccines, they contain a form of synthetic mRNA wrapped in polyethylene glycol nanoparticles that are used to precipitate ‘immunity’. The mRNA tells the body to make COVID spike proteins so that immune cells recognize them and will have the ability to mount an effective attack when presented with the real viral spike proteins. None of this matters, however, with regard to either vertigo or Guillain Barre or any other side effects observed with these products. This is not because they are not without risk, they carry plenty of risks, but because with so many fundamentally different products causing the same reactions, it cannot be the formulation of the product itself per se that is solely responsible for the illness. It has to be an interaction between the host and the product.

Calcium Channel Disruption: A Final Common Pathway?

In previous posts, I explored the role of calcium (Ca2+) channel disruption in the COVID heart and in thiamine deficiency/repletion protocols. In both cases, mitochondrial energy failure causes disruption in the sodium/potassium pumps, which then causes a rapid and uncontrolled influx of Ca2+ into the cells. In case of the cardiomyocyte, this leads to impaired contractility, cell damage, and if not resolved, cell death. I believe a similar process is involved in demyelinating disorders. Here though, instead of occurring in the heart, perhaps because of other genetics or environmental factors, the myelin sheaths of the axons are affected. Some evidence suggest that I am correct.

Mitochondrial dysfunction can leave the axon vulnerable as observed in acute and chronic stages of MS (red). It is hypothesised that the failure of the Na+/K+ ATPase, possibly due to mitochondrial dysfunction, can lead to increased sodium concentrations in the axoplasm. Reversal of the Na+/Ca2+ exchanger can ensue, resulting in toxic calcium levels and downstream processes with consequent axonal degeneration.

In either case, and perhaps across all negative vaccine and medication reactions, mitochondrial capacity broadly, and the regulation of Ca2+ influx more specifically, sits at the nexus. In other words, the capacity withstand a chemical insult, whatever that insult might be, is determined by the mitochondria’s ability to regulate Ca2+ response. If this is true, then by viewing each of these reactions is separate entities, we are missing the forests for the trees.

We Need Your Help

More people than ever are reading Hormones Matter, a testament to the need for independent voices in health and medicine. We are not funded and accept limited advertising. Unlike many health sites, we don’t force you to purchase a subscription. We believe health information should be open to all. If you read Hormones Matter, like it, please help support it. Contribute now.

Yes, I would like to support Hormones Matter. 

 

Another Day, Another Death

3198 views

Another Gardasil girl died last month. I didn’t know her, but her mother had written for us a few years back. My heart aches for her family and for all of the other families who have lost loved ones to pharmaceutical industry malfeasance. Sadly, her death is just one more in a long line of deaths attributable to this vaccine. For the industry that profits from this vaccine, her death means nothing.

No one, except her family and friends will suffer for her death. There will be no culpability from the industry that manufactures and distributes this vaccine, none from the governmental agencies that fail to address the safety issues of these medications, none from the doctors who push this and others vaccines and then dismiss the side effects outright leaving parents to navigate the resultant complex illnesses on their own. No one will admit responsibility. How can they? We have all have been fed a heavy diet of ‘vaccines are always perfectly safe’, that injuries and deaths are due to random chance, not the cocktail of toxicants proffered under the guise of herd immunity. Just unlucky I guess, the price to pay for the safety of others.

Vaccines are perfectly safe.

Really?

Forget, of course, that this is foolhardy and that nothing is perfectly safe.

Forget also that industry knows these vaccines are neither safe nor effective, having fudged the trials and post market research, spent billions on marketing to promote the faulty research, and no small sum on astroturfing campaigns, replete with vitriolic trolls and an echo chamber of paid ‘thought leaders‘.

Forget that 70% of major media budgets are funded by the pharmaceutical industry advertising, as are most medical associations, medical education, university and continuing, medical journals, and patient support groups. Health journalism too, receives its fair share of pharma funding.

Forget that the pharmaceutical industry spends more in lobbying politicians than any other industry, including defense.

Forget that the FDA is a revolving door to cushy industry jobs. Approve this or that drug and one is set for life once one’s government affiliation is over.

Forget too that FDA review panels are staffed with industry insiders and that FDA approves 96% of all applications. Can’t imagine how bad a drug has to be in order the FDA to reject it.

Forget that when vaccine side effects began to be recognized en masse during the Reagan administration, industry quickly colluded with governmental agencies to force vaccination and eliminate any liability for themselves. Enter the vaccine courts, where no matter the injury, no matter the negligence or malfeasance, the government foots the bill for industry. What an ideal business model; all products are always safe and if they aren’t someone else covers those costs. Liability? Responsibility? Nope.

Forget all of these things, and yes, vaccines can be considered perfectly safe, side effects ignored, and deaths considered unfortunate matters of coincidence.

Except they aren’t and we shouldn’t forget.

Young women are dying and/or are debilitated to the point of wanting to die, thousands of them, with this one vaccine alone. This is on top of the skyrocketing number of vaccine and pharmaceutical injured children. Did you know that 1 in every 68 children suffers with neurodevelopmental disorders; 1 in 68. That is a staggering statistic that should give us all pause, but mostly, it doesn’t. Neither does the fact that 70% of adults take at least one medication chronically, 50% take two or more, and 20% take five or more medications, or that toddlers represent the largest growing market for psychotropic medications – toddlers! Admittedly, toddlers can be a bit crazy, but do we really, truly believe that toddlers need antidepressants, stimulants, or worse yet, antipsychotics?

With all of these medications and vaccines, are we healthier?

Nope.

In fact, for the first time in generations, we are living sicker and dying younger. But no, we hold tight to the belief that pharmaceutical medicine is working and all of these injuries, illnesses, and deaths are flukes attributable to the vagaries of random chance.

It was a convenient dissonance while it lasted; still is for many. It allowed us to avoid the much starker reality of modern pharmaceutical medicine or modern living in general: that chemistry matters, that toxicants don’t just magically disappear once they enter the body (or the oceans), and that for all of our technological brilliance, we really have no frickin clue what the compound effects of all of these chemicals are. We really don’t. Heck, we don’t even know what most medications do. A study in the British Medical Journal found that only 50% of medications have sufficient data to suggest that they are likely effective. And since we don’t test most medications on women, we really have no idea whether any medications work or induce serious side effects in women.

Pharmaceuticals are chemical toxicants, plain and simple. They are poisons, albeit sometimes necessary poisons, but poisons nevertheless. We don’t call them poisons though. We call them medicines, but the fact remains, poisons don’t become less poisonous simply because we rename them.

Poisons, by their very nature, are designed to kill things, to block things, and otherwise usurp normal biological functions. Poisons do not ‘heal’. They supplant and they override. Neither do they become less poisonous simply because we take them in small doses. In fact, in many cases, it’s with the smaller doses, particularly when taken chronically, that we see the most devastating side effects, the complex multi-system ones that do everything but kill the individual outright. We are dissonant from these concepts, sometimes willfully. The chemistry is complicated, the disinformation dense, and if we’re truthful with ourselves, it’s easier not to know. Until it isn’t.

Knowing all of this, what do we say to the families who have lost love ones to vaccine injury or death or medication injury or death? How do we go about our daily lives knowing the science is corrupted, arguably with intention, and that more will suffer as a result?

I don’t know the answer to either of these questions. All I know is that as a mom, I feel your loss and I am sorry.

We Need Your Help

Hormones Matter needs funding now. Our research funding was cut recently and because of our commitment to independent health research and journalism unbiased by commercial interests we allow minimal advertising on the site. That means all funding must come from you, our readers. Don’t let Hormones Matter die.

Yes, I’d like to support Hormones Matter.

Image by Manie Van der Hoven from Pixabay.