vaccines

The Vaccine Debate: Where is the Empathy?

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Of Peanut Allergies and Petulance

A few weeks ago, a fellow social media acquaintance posted an article about peanut allergies in children. The article argued that no peanut butter sandwich is as important as a child’s life, so she urged her fellow moms not to bring peanut items to school if a classmate had a known peanut allergy. I read it: it was heartfelt and very sensible. I am of the opinion that my daughter can certainly live without peanut butter sandwiches at school. Her school is nut free, and never once has it inconvenienced me in the slightest. When I found out about the nut-free rule, my first thought was “Wow. I’m so glad that I do not have to worry about my daughter encountering such a dangerous allergy situation all the time–that must be really hard for those parents.” Apparently, that’s not such a common response. Read any of these articles on moms talking about peanut allergies and you will find comments from parents reacting in ways that range from annoyed to down-right cruel. Parents protesting that “Kids should learn to navigate their allergies in the real world” and “My child won’t eat anything else!” This poor mother is sitting there having to worry about one sticky peanut butter finger touching a door knob and her small child dying in a matter of minutes from anaphylaxis after touching that door knob. Think about that for a second: HAVING TO WORRY THAT YOUR CHILD WILL DIE EVERY SINGLE DAY AT SCHOOL FROM PEANUT BUTTER.  Thinking about that is enough to make my heart bust open with torturous sadness for that parent. The lack of empathy in those responses was astounding. In some cases, down right sociopathic.

You may be on board with the peanut butter argument, agreeing that we should have empathy for children with peanut allergies. Those kids didn’t choose their allergies, and their parents have to worry that their children will die from a product that is nearly ubiquitous in our existence. You may be one of the parents that gets that, and that’s great. But the conversation took an even darker turn, and that is what I want to really talk about in this article. One respondent wrote something to the effect of, “Why do we just have to worry about peanut butter sandwiches when there are stupid, irresponsible parents who let their child come to school unvaccinated and put our children at risk of death every day.” If you’ve read this article, you can imagine that struck a nerve with me. Although I feel like my response to that comment was both warranted and respectful, it never does any good but open Pandora’s Box, leaving me tired, discouraged, helpless and hopeless. WHY? Lack of empathy.

Vaccine Vitriol: A Pattern of Predictable Disdain

There’s a group of people in our society that is marginalized beyond belief in the most cruel and unusual ways: vaccine injured children and their families. Now before you stop reading, thinking I am some crazy “anti-vaxxer” about to do some “pro-vaxxer” bashing, please know that is not going to happen here. In fact, I am attempting to do exactly the opposite. The vaccine argument is one of the most contentious and heated debates I’ve ever seen. I’d be willing to go out on a limb and say it is worse than probably any other political issue to date: even more so than gun control or immigration.

In any vaccine discussion, it is common for phrases like “you should have your kids taken away and go to jail” and “you’re an idiot who believes in pseudoscience” to fly around the conversation. To be honest, there’s a lot of self-righteousness and indignation sometimes on both sides of the issue. So what is going on here? Why can’t we have a civil conversation about vaccines, like, EVER?

Well, I’m a psychologist, so all the obvious answers (to me) ran through my head: cognitive dissonance, belief perseverance, etc. Yes, it’s well documented in psychological science that people cling tight to their beliefs even in the face of overwhelming contradictory evidence, but these things don’t really account for why people can be so darn MEAN to each other in the process. Then (as I usually do), I started ruminating on how, at some level, every single thing that human beings do is explained by consciousness. Human beings are a product of their minds, and our minds are set up to run in very predictable ways. Human brains are pattern seekers; they constantly put things into groups or categories. Every piece of stimulus information we encounter (what we see, hear, touch, feel, taste), is organized in the brain in a way that helps us put things into logical order.

Information is stored in our long term memory in something called a semantic network, where similar pieces of information remain connected together in our brains. We create schemas, which are “templates” for objects and situations that become stored in our memory. These things help us predict and anticipate things we will encounter in the future. In other words, these processes help us navigate a world filled with overwhelming amounts of stimulus information. Usually, this works pretty well for getting around this complex world, except that life is not black and white, and dealing with the gray areas require much more effortful processing.

What does this have to do with meanness and lack of empathy? If our minds are naturally inclined to place things into groups, then that’s part of the reason that it’s so easy to cling to dualistic thought: right vs. wrong, bad vs. good, in-group vs. out-group, winner vs. loser. Not only are our brains pattern seekers, but we’re also social animals that seek out similar others. Both of these things help create a large “us” vs. “them” dynamic. Psychological science has also shown that we tend to have more empathy for those who are similar to us than dissimilar. In other words, when “us” encounters “them”, our brains are more inhibited from producing empathetic responses. Moreover, the anger that arises from our values being challenged activates our amygdala (our brain’s alarm system) which competes against our pre-frontal cortex (involved in self-control and rational thought). Combine all of that with the deindividuation (loss of self-awareness in a group) of the social media environment, and you’ve got a recipe for cruelty and indignation.

Beyond Us Versus Them in the Vaccine Debate: Empathy First

How can we unravel these barriers when it comes to the vaccine argument? One word (here it is again): Empathy. No, it’s not the dominant response in this situation, but research has also shown that we can call upon our executive functions like self-control and exert them upon will. It’s tough, and it depletes us when we do it, but it can be done. We need to approach these conversations by first trying to willfully control our immediate anger that results from confronting information that challenges our beliefs. Yes, that challenge is uncomfortable, but by taking a few minutes to let your mid-brain calm down and execute willful self-control, you’ll be better prepared to try to understand the other side of the argument.

One very smart commenter in that social media conversation, who was actually the first person to acknowledge that maybe I wasn’t crazy after all for speaking out against vaccinations, suggested that instead of eliciting anger and defensiveness, attempting to induce empathy with rational thought might be a better strategy. She suggested asking yourself, “Why would someone choose not to vaccinate their child?” or “Why would someone want to force everyone to vaccinate when they know some children have been injured by vaccines?” If you’ve really been able to put your anger aside (at least temporarily) then you’ll realize the answer to both questions is exactly the same: They want healthy children. Suddenly, it’s not “us” versus “them” anymore, it’s just “us”. We all want the same thing, we just have vastly different feelings about how to accomplish it.

This person also made a point that was the driving reason behind writing this article. She said something about how being “right” isn’t a strategy if you want to change the hearts of people that disagree with you.  I’ll admit, that’s all I have ever been trying to do: be right. The need to be right comes from a real and raw place deep down in my heart. I watched my daughter fight a chronic auto-inflammatory disease that was triggered by vaccinations. I held her while she suffered. I fought for her when doctors couldn’t figure it out. I’m the one who read hundreds of scientific articles, pored over her lab results, tracked every symptom, found the patterns, and put the puzzle pieces together. I demanded the referrals, I found her cure, and she’s currently in remission–not because of what her doctors knew but because of what I KNEW.  When you experience something like that, it’s really hard to hold on to the age-old notion that “doctors know best.”

When the vaccine debate emerges and I tell people our story, at best I will get “I’m sorry for what happened to your daughter, but that is rare” and at worst, “I highly doubt your daughter’s condition was triggered by vaccines, vaccines are a scapegoat for the onset of many genetic conditions”.  Neither of those responses is empathetic. I consider myself lucky that my daughter is in remission, but my heart breaks knowing that there are parents out there whose children are severely disabled or have died as a result of vaccines, and those are the responses they get from others.

On the other hand, I need to take a moment and practice what I’m preaching here. I need to show some empathy those folks who so valiantly defend vaccines, and I’m going to ask my vaccine-questioning friends to try and do the same. I understand why people defend vaccines. I really do. I understand the fear of a tiny little baby contracting a horrible disease that could end in their death and being angry thinking that some kid who could have been protected from that disease could be the culprit that led to your child’s death. That is absolutely terrifying and a real phenomenon that has happened in this world. I mean, all you have to do is go to the mall and see that people are coughing and sneezing, EVERYWHERE. The risk is real. I understand because I, too, share that fear. I have been exposed to information that has lessened that fear to some degree, but I still have it.  I understand that the rational and logical thing to do is adopt the mainstream position of highly respected doctors, scientists and health organizations who have had intense training in science and medicine. I can understand how ridiculous it sounds to think that all of these experts are somehow wrong or involved in some kind of grand conspiracy to cover up the idea that vaccines are highly dangerous or ineffective. In fact, I’m willing to say that this position is the logical position. I’m not going to tell anyone that believes this that they are wrong. I’m going to tell them that I understand. I not only understand, but I want to have faith in doctors and research and the CDC, too.

Some Things You Cannot Un-Know: The Corruption Runs High, But Not Necessarily Deep

Now, my vaccine defenders, it’s your turn. There is only one thing that has separated your position from my own: life experience. I cannot have faith in these doctors and organizations because they have failed me and they failed my daughter in very real, life-changing ways. When you or your child has been injured by something that you were told was safe, you can’t just shrug your shoulders and say, “Well I guess everything has risks and my child was one of the rare ones.” Nope. You say “How could this have possibly happened?” You start digging. You quickly find out there are thousands of research articles that contradict the mainstream opinion, even entire textbooks. You find out that there are thousands of doctors and scientists shouting from the rooftops about how the risk of what happened to your child is not uncommon. You find out that there has been so much corruption and cover-up in organizations like the FDA and CDC that congressmen are shouting on the congressional floor for our government to do something about it—but nothing ever gets done. You find out that pharmaceutical companies have all the money and the power and that they own the media and that’s why these dissenting scientists aren’t featured on the news. You find out the pharmaceutical companies also fund the research, pay the editors of the journals, pay doctors money to speak about their products, and even influence the head of the FDA.

Suddenly the once illogical argument that the mainstream is wrong is not so illogical after all. It’s not a grand conspiracy, it’s the influence of money and greed forcing the direction of science and medical opinion at the very top of the chain, and all those underneath that aren’t being funded simply go along with the “respected” opinion of those at the top. For those underneath who have discovered the truth, they have figured out that publicizing dissenting opinions runs the risk of destroying both their careers and reputation. The safe choice is to continue with the status quo. That’s how it happens. That’s how thousands of children and adults can be injured by pharmaceuticals, and the rest of us stand back and let it happen. Once you know this information, you can’t un-know it. It changes you.

Go Beyond the Feedback Loops: Walk in Another’s Shoes

In many ways experiences hand us our reality, but in many ways we also create it. The things we Google appear on our Facebook feed; the things we like on Facebook are tracked and used to send us similar material. It’s easy to see how once we adopt a position it’s constantly being reinforced by more and more exposure to the same information. It’s unlikely that we ever truly expose ourselves to the other side of any argument—but that may be the key in fostering the empathy we need to drive the change we seek in the vaccine debate. Psychological science has demonstrated the social influence of reciprocity, where one concession leads to the concession of the other side. This is a powerful psychological phenomenon. So, I’m conceding. Instead of begging vaccine-defenders to listen to us and focusing on trying to be right, let’s for one second, focus on their position. Put yourself in their shoes. Show them that you understand that they have fears for their children, too. Showing empathy is the only way they will show us that in return. Being right cannot be our strategy, because it’s not their minds we need to change—it’s their hearts.

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Obesity and Childhood Vaccines: Is there a Connection?

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The staggering increase in obesity affecting mainly people of the industrially developed world is an indisputable fact. Researchers have put forward a number of ideas of which overeating and/or eating too much sugar/carbohydrates and fats are the most popular. However, orthodox medical research points to some other factors and phenomena starting with a growing incidence of infantile and pediatric hyperinsulinemia.

Infantile hyperinsulinemia is sometimes considered a rare congenital disorder where excessive insulin secretion creates a state of hypoglycaemia – low blood sugar. Severe hypoglycemia in the newborn can lead to a myriad of health issues including severe neurological handicaps and seizures. The symptoms are recognized generally at around six months of age and are believed to develop in 1/50,000 births.
In regions where consanguinity are common the rate may be as high as 1-2/500. However, there are non-genetic, iatrogenic (medically induced) mechanisms of hyperinsulinemia that must be considered also.

An emerging body of evidence suggests a connection between infantile hyperinsulinemia and the administered vaccines, the use of antibiotics and other medical and environmental factors. The timing of infant vaccines, in particular, corresponds closely to the recognition of infantile hyperinsulinemia. Could there be a connection between vaccines and/or antibiotic use and insulin dysregulation in infants and children? Moreover, would this also predispose children to obesity later in life?

Vaccine Induced Hyperinsulinemia?

With the pertussis portion of the DTP vaccine (diphtheria, tetanus and pertussis; and now DTaP [aP=acellular]) pertussis vaccine, there have been longstanding questions regarding safety. In 1978 Hannik and Cohen wrote, “There is a considerable concern about the reactions that sometimes occur in children following the injection of pertussis vaccine. Reactions have been observed and reported since 1933 (1) and range from the slightest minor reactions to status convulsivus resulting in permanent cerebral damage.”

Hannik and Cohen’s review cites a number of studies identifying adverse reactions to the pertussis portion of the vaccine and a relationship to insulin homeostasis, including: Parfentjev and Schleyer (1949), Szentivanyi et al. (1963) Tabachnik and Gulbekian (1968), Tabachnik and Gulbekian (1969). Respectively, these studies dealt with the influence of histamine on the blood sugar level of normal and pertussis vaccine sensitized animals (rats and mice), adrenergic changes due to pertussis [vaccine], insulin, glucose and free fatty acids and encephalopathy following pertussis vaccine prophylaxis. The pertussis vaccine proved to be the principal precipitating pathogen in all cases.

Hannik and Cohen (1978) wrote, “Infants injected with DTP-Polio vaccine with a pertussis component of 16 International Opacity Units per dose showed slight but significant elevation in concentration of plasma insulin and temperature.” They concluded that the phenomena (i.e. the elevation in concentration of plasma insulin and increased temperature) are not interrelated. They suggested that “infants who show serious reactions following pertussis vaccination suffer from a failure to maintain glucose homeostasis.” They also noted, “low blood sugar level and extremely low CFS-glucose concentration have been reported in children who developed convulsions 3 and 36 hours after receiving pertussis vaccine.”

A few years later, Katada and Ui (1981) wrote, “Islet-activating protein is a new protein isolated from the culture of Bordetella pertussis as one of the pertussis toxins. It interacts with islet cells slowly to give rise to striking reversal of alpha-adrenergic inhibition cAMP accumulation in, a consequent insulin release from the islet cells.” In other words, a protein toxin within the pertussis portion of the DTP/DTap vaccine was found to initiate insulin release, providing additional evidence connecting the vaccine to infant hyperinsulinemia.

Deranged Glucose Metabolism in Childhood

Interestingly, Zametkin et al. (1990) demonstrated that adults with hyperactivity of childhood onset suffer derangement of cerebral glucose metabolism affecting the prefrontal cortex and superior prefrontal cortex, the parts of the brain that control attention and motor activity. Could the pertussis protein toxin that activates insulin release identified by Katada and Ui (1981) be responsible for childhood derangement in sugar metabolism and not the consumption of sugar, as such, that is implicated? Even though the authors considered the cause of the altered glucose metabolism unknown, it is clear to me that impaired glucose homeostasis may be a result of childhood vaccination. The consequences of this impairment may then be related to many of the conditions plaguing modern society, including obesity. Indeed, the product insert for Tripedia Sanofi Pasteur DTaP vaccine lists autism (SIDS and other serious reactions) detected during post-marketing surveillance.

From Vaccines to Hyperinsulinemia to Obesity

Hughes (1997) demonstrated a significant increase in both the height and weight of the 5 to 11-year old English and Scottish children and called for an urgent need to realistic intervention to reduce obesity in this population.

Freedman et al. (1997) described secular increases in relative weight and adiposity among children over two decades, from 1973 to 1994 in a biracial community of Ward of Washington Parish, Louisiana, USA.

According to Medical Observer (2005; May 12), “Alarming levels of hyperinsulinism, fatty liver, dyslipidaemia and other complications are present in Australian primary school children with high body mass index (BMI)”.

According to Dunne et al. (2004), “hyperinsulinemia promotes hepatic and skeletal muscle glucogenesis, which decreases the amount of free glucose available in the blood stream and results in suppression of the formation of free fatty acids. Fatty acids do not cross the blood brain barrier and cannot be used by the brain as an energy substrate. The combination of hypoglycaemia, reduced fatty acids availability for cardiac and skeletal muscle metabolism and reduced ketones for cerebral metabolism result in adrenergic and neuroglycopenic symptoms with severe neurological dysfunction. Seizure activity will also manifest. Repeated episodes of severe prolonged hypoglycaemia can result in permanent neurological damage, including developmental delay, mental retardation, and/or focal CNS deficits.”

Although the research groups noted above identified hyperinsulinemia in the studied populations, none investigated the role of the administered vaccines, in the induction of hyperinsulinemia. Given the research highlighted previously, it seems plausible that protein toxins contained in the pertussis vaccine are capable of evoking hyperinsulinemia and by way of association may be responsible for the increasing rates of childhood obesity. To that end, Smith and Furman (1988) wrote, “Pertussis vaccine, pertussis toxin, and the alpha-adrenoreceptor blocking drug phentolamine augment glucose-induced insulin secretion. The present study was carried out to determine the relationship between the action and the ability of these agents to prevent the inhibitory action of adrenaline. Pertussis vaccine augmented glucose-induced secretion in rat islets ex vivo and prevented the inhibitory actions of adrenaline and clonidine.”

Antibiotics and Obesity

Another class of medications – antibiotics – might also be linked to the increase in childhood obesity. Antibiotics are widely prescribed for a great number of conditions. Most children suffer a series of ear infections and lower respiratory and urinary infections in the first year of life after vaccination, as documented by Craighead (1975) and may, as a rule, be given several rounds of antibiotics.

Antibiotics are used prolifically in the animal food industry to enhance the protein (flesh) production and weight in animals. These have the same effect on children as they have on young food animals: antibiotics make them fat and muscular.

Garly et al. (2006) unwittingly documented the fattening effect of antibiotics in children in a developing country. They wrote, “The group that received prophylactic antibiotics had less pneumonia and conjunctivitis and has a significantly higher weight gain in the months after inclusion.”

Conclusion

Although not consistently considered a culprit in the widespread childhood obesity epidemic, iatrogenically impaired infant and childhood glucose homeostasis may be a contributing factor. Administration of DTP/DTaP and possibly other vaccines, alone or together with antibiotics could predispose children to chronic states of impaired insulin metabolism and glucose regulation irrespective of dietary considerations.

References

Kumaran et al. (2010). The clinical problem of hyperinsulinemic hypoglycemia and resultant infantile spasms. Pediatrics; 126(5): e1231-1236.

Hannik and Cohen. 1978. Changes in plasma insulin concentration and temperature of infants after pertussis vaccination. Third International Symposium on Pertussis. (Part 3): 297-299.

Parfentjev and Schleyer. 1949. Influence of histamine on the blood sugar level of normal and sensitized mice. Arch Biochem. 20: 341-346.

Szentivanyi et al. 1963. Adrenaline mediation of histamine and serotonin hyperglycemia in normal mice and the absence of adrenaline induced hyperglycemia in pertussis sensitized mice. J Infect Dis; 113: 86-98.

Tabachnik and Gulbekian. 1969. Adrenergic changes due to pertussis, insulin, glucose and free fatty acids. Eur J Pharmacol, 7(2): 186-195.

Toshiaki Katada and Michio Ui. 1981. Islet-activating protein. J Biol Chemistry; 16 (August 25): 8310-8317.

Zametkin et al. (1990). Cerebral glucose metabolism in adults with hyperactivity of childhood onset. NEJM; 323 (November 15): 1361-1366.

Hughes et al.(1997). Trends in growth in England and Scotland 1972-1994. Arch Dis Child; 76:182-189.

Freedman et al. 1997. Secular increases in relative weight and adiposity mong children over two decades, from 1972 to 1994, residing in Ward 4, Washington parish, Louisiana. Pediatrics; 99(3): 420-426.

Smith and Furman. 1988. Augmentation of glucose induced insulin secretion by pertussis vaccine, phentolamine and benextramine: involvement of mechanism additional to prevention of the inhibitory actions in rats. Acta Endocrinologica; 118:89-95.

Dunaif et al. 1989. Profound peripheral insulin resistance, independent of obesity in polycystic ovary syndrome. Diabetes; 38(9): 1165-1174l

Nestler et al.1990. A direct effect of hyperinsulimemia on serum, sex hormone-biuding globulin levels in obese women with the polycystic ovary syndrome.

Gambineri et al. 2002. Obesity and polycystic ovary syndrome. Journal of International Association for the study of obesity. 26(7): 883-896.

Scott et al. 1997. Characteristics of youth-onset of non-insulin dependent diabetes mellitus and insulin-dependent diabetes mellitus at diagnosis. Pediatrics; 100: 84-91.

Dunne et al. 2004. Hyperinsulinism in infancy. From basic science to clinical diseases. Physiology Rev; 84: 239-275.

Valdyula et al. 2006. Platelet and monocyte activation by hyperglycemia and hyperinsulinemia in healthy subjects. http://informahealthcare.com/doi/abs/10.1080/09537100600760814: 17(8): 577-585.

Burghen et al. 2013. Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease. J Clin Endocrinol and metabolism; 50 (issue 1). Published online July1, 2013,

Takizawa et al. (2001) Gender differences in the relationships among hyperleptinemia, hyperinsulinemia, and hypertension. Clinical and Experimental Hypertension; 23(4): 357-368.

Hussain et al. 2004. Infantile hyperinsulinemia associated with enteropathy, deafness and renal tubulopathy: clinical manifestations of a syndrome caused by a contigous gene deletion located on chromosome 11p. J Pediatr Endocrinol Metab; 17(12): 1613-1621.

Michaud et all; 2014. Acetaminophen-induced liver injury in obesity and non-alcoholic fatty liver disease. Liver Int; 34(7): e171-179. doi.1111

Weiss. 1975. Acetaminophen, a potential pediatric hazard. Pediatrics; 52 (6): 883.

Goulding 1973. Acetaminophen poisoning. Pediatrics; 52(6):883-885.

Craighead 1975. Report of a workshop: Disease accentuation after immunisation with inactivated microbial vaccines. J Infect Dis; 1312 (6): 749-754.

Garly et al. (2006). Prophylactic antibiotics to prevent pneumonia and other complication after measles, community based randomised double blind placebo controlled trial in Guinea-Bissau. BMJ, doi:10.1136/bmj.38989.AE published 23 October 2006.

Wal-Mart to Offer HPV Vaccine

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Now, in addition to low priced groceries and other goods, your local Wal-Mart will offer nurse kiosks ready to inject you or your child with a variety of vaccines. Wal-Mart is joining other stores, like Walgreens and CVS, in offering walk-through health clinics. According to recent reports, Wal-Mart will be the first to offer the controversial HPV vaccines Gardasil and Cervarix.

At Hormones MatterTM, we have written a lot about Gardasil and the HPV vaccine questioning its safety. Gardasil: Miracle or Deadly Vaccine?, Is Gardasil Mandated in Your State?, What About the Pap Smear?. For a very heartbreaking story at the dangerous side effects of this story please read A Ruined Life from Gardasil. HPV is a very common virus that many experts believe the body can fight off by itself; with annual pap smear tests a doctor can easily catch and remove any abnormal cells before they become cancer.

The trend of selling direct-to-consumer vaccines, like that of selling over-the-counter medications is time-saving and logical on the one hand, but is troubling on the other, especially with vaccines and medications that have less than stellar safety profiles. Any product sold direct-to-consumer comes with the false presumption that it is entirely safe. Indeed, we have consumer protection agencies to ensure that this is the case with most products. Consumers often mistakenly assume that over-the-counter medications are safe because there is a consumer protection agency protecting their well-being, otherwise the product would not be on the market. Unlike a toy with a choking hazard or a product batch with a chemical contaminant, where the cause and effect are obvious and easily remedied with recall, the direct side-effects or adverse reactions of medications or vaccines are difficult to recognize and more difficult to prove, even under the most regulated of circumstances. When medications or vaccines are sold over-the-counter, it is nearly impossible.

The over-the-counter vaccines effectively remove any ability for physicians, researchers or patients identify side-effects. Selling over-the-counter vaccines is a boon to the pharmaceutical industry, however. With this single move the industry can sell more vaccines, the vaccines become safe in the eyes of the consumer while the industry removes the ability to prove otherwise, and a brilliant, albeit less than ethical, corporate strategy is pushed on consumers.

What do you think, should vaccines be available at the local pharmacy?

Hormones MatterTM is conducting research on the side effects and adverse events associated with Gardasil and its counterpart Cervarix. If you or your daughter has had either HPV vaccine, please take this important survey. The Gardasil Cervarix HPV Vaccine Survey.