As part of my work here, I am regularly confronted with desperately ill individuals who have seen dozens of physicians over the course of many years only to have their health continue to decline. Among the more frustrating aspects of this work is the failure of these physicians to assess and address the most basic […]
There is ever increasing evidence that energy metabolism is involved in the causation of cancer. A phenomenon known as the Warburg effect has been known for a century and was thought by Warburg to be the cause of cancer. To summarize this effect, normal cells primarily produce energy by the consumption of oxygen in a […]
I have been studying thiamine metabolism since 1969 when I published the first case of thiamine dependency: Intermittent cerebellar ataxia associated with hyperpyruvic acidemia, hyperalaninemia, and hyperalaninuria. The case involved a 6-year old boy experiencing recurrent episodes of cerebellar ataxia (a brain disease resulting in complete loss of a sense of balance). These episodes, occurring intermittently, […]
For DES Daughters, Conception and Pregnancy Are DifficultMy first pregnancy, now 30 years back, was difficult. I am a DES daughter and after years of trying to conceive naturally, we tried in-vitro fertilization (IVF), which was pretty new at the time. The first IVF attempt led to a miscarriage. The second IVF attempt was successful […]
Ever think about zooplankton? Yea, me neither. Heck, until recently I had only a vague understanding of what these creatures were. I thought they were sea plants of some sort. Perhaps the ‘zoo’ in the name should have clued me in. It didn’t. Go ahead, you can laugh. My knowledge of fifth grade ocean biology […]
In the Wall Street Journal, August 14, 2018, Your Health, written by Sumathi Reddy, recorded the case of a 34-year-old pregnant woman who went to the hospital with shortness of breath and dizziness. Doctors decided that they were “pregnancy-related symptoms and nothing to be overly concerned about”. The column goes on to say that eight […]
In US population studies, the prevalence of migraine is approximately 18% in women and 6% in men. About 90% of sufferers have moderate or severe pain and 75% have a reduced ability to function during the headache attacks. One third require bed rest during an attack. A study at the Mayo Clinic showed the incidence […]
Over the last several months, I have been fascinated by the fuel preferences of the mitochondria in the different organs of the body. It seems that the mitochondria in each organ system have specific fuel preferences. The muscles like protein and carbs, the heart likes fatty acids, and the brain has all sorts of fuel […]