lupus

Birth Control: The More Things Change

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The medical and drug industries are notoriously arrogant. While each generation of practitioner may acknowledge the errors of the past, they continue down the path of contemporary errors with an inexplicable faith in their own omniscience. Unfortunately, the magnitude of collateral damage from these mistakes has tended to grow exponentially with each passing generation, but no medical mistake (so far) can match the horrific toll still being wrought by birth control.

Time After Time

We aren’t terribly far removed from doctors promoting the health benefits of smoking cigarettes. Nor, in the grand scheme, has it been that long since leeches and bloodletting passed for cutting edge technology – or perhaps sucking edge.

Reflecting on errors of the past shouldn’t imbue today’s doctors with a sense of supreme knowledge. Instead, it should give them pause to wonder what tomorrow’s doctors may find laughable about their current practices.

The modern doctor may laugh at the doctor who promoted cigarettes, while that doctor laughed at those who promoted lobotomies, as those doctors laughed at snake oil salesmen.

While today’s doctors may have largely discarded lobotomies and leeches, the part that sucks most is that we seem to have lost the art of doing away with antiquated medical dogmas once they’ve been proven unsafe… at least, until lawsuits and settlements tip the balance.

Mea Culpa

The drug companies sit in the shadow of a well-documented history of business practices which promote profits-over-people. Examples like thalidomide, DES, and Vioxx should be enough to call into question this industry’s trustworthiness. Whether it’s greed or hubris, the industry consistently releases new drugs with authoritative assurances regarding their safety, and it’s rare to see them back down from these assertions – even as the courts begin to say otherwise.

So, consider how rare this admission was from Dr. Harry Rudel, one of the developers of The Pill:

The pill is something we entered into with the best of faith, something we truly believed affected only ovulation and fertility. It was a relatively small dose of a drug, and it appeared that it was not affecting anything except fertility. Then as we began to look, we began to see that we are influencing many systems in the body.

Change Is in the Air (Or Is It?)

Hormonal birth control remains the one persistent drug that seems to be made of Teflon – nothing sticks. It has been linked to dramatic rises in diseases affecting everything from the heart to the liver. With each newly identified risk, ‘experts’ assure us the benefits still outweigh the risks, and, somehow, that seems to be enough to just make it go away.

At some point, we (meaning ALL of us around the world) need to stop accepting this myopic minimization of all these disparate negative consequences. Sincerely, we are all stakeholders in this fallout, which has grown to a scale that would now be impossible to measure.

Recently, thoughts about the sheer magnitude of this tragedy hit me like a gut punch. I’ll explain what happened and share three scenarios that should be enough to make us seriously rethink our position on hormonal birth control.

Changes in Lupus

I recently participated in a webinar with Sara Harris and Rebecca Asquith from Follow Your Flow, during which I discussed the dramatic evolution of lupus in a relatively short amount of time. I explained how lupus used to be an old person’s disease. Then, with the rollout of birth control, doctors were alarmed that they began to see young women coming into their clinics with lupus.

Fifty years later, lupus is thought of primarily as a young woman’s disease. The tides have shifted so significantly in such a short amount of time that what used to be the norm is now called ‘late onset lupus.’ Women in their 40s and 50s are surprised to learn they can even develop lupus at ‘such a late stage of life.’

Shortly after the webinar, I encountered one of the attendees, who told me that her husband’s sister had been diagnosed with lupus in 1966 at the age of 17. Her specialist had been “so in awe of her condition that she attended presentations/lectures with him.” She died at the age of 24. While it isn’t certain that she was on The Pill, the timing in relation to the wave of young women who suddenly began developing this old person’s disease makes it very plausible.

Thinking of this 24-year-old woman who died so many decades ago struck me. Her family never even knew that her lupus could have been connected to birth control. How many other young women have been struck down so young because of these potent drugs, and nobody was ever the wiser? Please – pause for a second and ponder that – what is the potential body count of young women who have died in the past 60 years from lupus, a stroke, a pulmonary embolism, a heart attack? How many of them were buried with their family wondering why she had the misfortune of being taken so young – without ever knowing how easily it could have been prevented?

Changes in Breast Cancer

Unfortunately, lupus isn’t the only disease that looks different today than it did when hormonal birth control was introduced. Just as expert testimony at the Nelson Pill Hearings (1970) revealed concerns about changes in lupus, other experts testified about how The Pill would likely contribute to breast cancer numbers. One of those experts was Dr. Max Cutler, who warned that The Pill should never be used chronically. He called it a cancer time bomb whose fuse could be 15 to 20 years.

Dr. Cutler practically guaranteed we would see a dramatic rise in breast cancer. At that time, 1 in every 20 women would be diagnosed with breast cancer at some point in her life, which equated to about 75 to 80,000 diagnoses each year.

This year (2021), we expect to see over 281,000 breast cancer diagnoses, and 1 in every 8 women will be diagnosed at some point in her life. That’s an increase of over 250-percent!

Many doctors now dismiss the breast cancer scare as old news attributed to the first-generation pills. They assume the newer ‘low dose’ formulations resolved that problem (because that’s what they’ve been taught). However, a recent Danish study confirmed that women on these newer formulations still faced a 20-percent greater risk of developing breast cancer than women who didn’t take hormonal birth control.

Changes in Multiple Sclerosis

As I’ve written previously on Hormones Matter, multiple sclerosis is a naturally discriminatory disease in terms of gender because of how particular cytokines within the immune system interact with estrogen. This is true of many autoimmune diseases.

So, if the disease has a natural gender bias, how do we know what role birth control is playing in its incidence?

In 1940, well before the introduction of hormonal birth control, twice as many women as men had multiple sclerosis in the US. However, by the year 2000, as the number of overall cases grew, the gender gap also widened – 4 out of every 5 diagnoses were women. That represents a 50-percent change in the gender bias over each decade.

Epidemiological studies from other developed countries revealed similar shifts in the gender ratio over the same timeframe. For example, a Danish study found that men experienced a 30-percent rise in their cumulative incidence rate (CIR), while the CIR for women more than doubled.

The Epidemiological Significance of Rapid Change

Commenting on some of the multiple sclerosis studies mentioned above, Sreeram Ramagopalan, Ph.D., research fellow at University of Oxford, said this:

A change that occurs within a century is too short a time for a genetic cause. This suggests that environmental factor(s) are at work in a sex-specific manner.

Any of these examples alone should be enough to make us feel as if we’ve been collectively punched in the gut. Hopefully, it will eventually spark an epidemiological curiosity in a researcher somewhere.

If you happen to know of an epidemiologist who’s trying to figure out what the sex-specific environmental factor(s) might be, could you direct them my way? I’ve got a thought or two I’d be willing to share.

#1
In the Name of The Pill

37 customer reviews

In the Name of The Pill*

by Mike Gaskins

The FDA approved The Pill despite it not being proven safe. Today, it has been linked to everything from blood clots and cancer to lupus and Crohn’s disease — and still has not been proven safe.
This book explores the medical and historical disconnects that brought us to this point.




 Price: $ 17.95

Buy now at Amazon*

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Last updated on October 21, 2023 at 9:38 pm – Image source: Amazon Affiliate Program. All statements without guarantee.

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More people than ever are reading Hormones Matter, a testament to the need for independent voices in health and medicine. We are not funded and accept limited advertising. Unlike many health sites, we don’t force you to purchase a subscription. We believe health information should be open to all. If you read Hormones Matter, like it, please help support it. Contribute now.

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Birth Control Ain’t Right (But Neither Should It Be Left)

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I’m writing this article with all the trepidation of someone walking into a Thai restaurant with a peanut allergy — knowing it could go horribly wrong.

I want to discuss politics. More precisely, I want to talk about a political fight by apolitical means. When it really comes down to it, hormonal birth control and women’s health transcend politics – or at least they should. It’s easy to lose sight of that in today’s political climate.

Lupus and Birth Control

An item came across my news feed this morning that caught my eye. It wasn’t a news story, but a letter to the editor of a coastal newspaper. The writer mentioned the increasing incidence of lupus in young women caused by hormonal contraceptives (the keywords that landed it in my newsfeed). Wow! That’s a connection very few people have made. I wanted to read more.

But when I opened the letter, it was a political diatribe from a woman who was all over the map. She talked about Republicans using the Honduran caravan to get votes. She blamed the caravan on overpopulation caused by poverty stemming from a Latino machismo perpetuated by the Catholic Church. She accused conservatives of trying to outlaw birth control. I was with her when it came to the facts (or fact), but she lost me in her rhetoric – and it’s not even about whether I lean Right or Left. Let me explain:

  • The increased incidence of lupus in young women on birth control is a fact. We should all be concerned about this and be engaged in dialogue on how to fix it.
  • Politicization of the Honduran caravan is opinion. In fact, the rhetoric has gone both ways. Depending on where you get your opinion-news, you could believe the caravan was likely being funded by either Donald Trump or George Soros.
  • The overpopulation-poverty-machismo-Catholic theory is opinion. I don’t even know where to begin, but I guess there’s always a way to blame the Catholic Church when you’re talking about birth control.
  • Conservatives trying to outlaw birth control is opinion. I know some will argue that it’s a fact, but I haven’t seen any evidence of this. Living in Texas, I have a number of ultra-conservative friends, and I have never had anyone approach me with the suggestion that we outlaw birth control – and that’s with knowing how much I hate The Pill. To the contrary, I’ve actually been accused of being anti-capitalism because of my attacks on the drug industry and birth control.

Divided We Fall

Women’s health is worth the fight! Lupus induced by birth control is not only the lede; it’s the story. If we can agree on that, then I really don’t care who you think funded the caravan. If we can unite in agreement that birth control is harming women by means of breast cancer, blood clots, Multiple Sclerosis, suicide, infertility, Crohn’s Disease, diabetes… should it really matter to me whether I’m linking arms with a Republican or a Democrat?

I know it may be pie-in-the-sky to think we can rise above political affiliation in this day and age, but we should. This has been going on for far too long.

As far back as 1970, the Nelson Pill Hearings revealed many of the horrible complications linked to birth control. The news coming from the hearings was so devastating that women across the country began to call their doctors asking to be taken off The Pill. If you view politics through a lens of only the past decade or so, it might seem hard to believe that it was a Democratic senator who chaired the hearings, and it was a young Republican senator from Kansas who defended The Pill. Sen. Bob Dole virtually attacked every doctor who testified about troubling side effects.

Ben Gordon, who was Sen. Gaylord Nelson’s lead staffer said, “Dole was on our committee, and when he came, there was no question he was representing the industry.”

The industry has always been organized in promoting and defending its product. Unfortunately, the era surrounding the Nelson Pill Hearings is as close as the opposition has ever come to being organized and unified.

United We Stand

The hearings brought together doctors from all different specialties who felt The Pill had been forced upon them despite insufficient testing. Suddenly, the media was paying attention to doctors, journalists, and authors who had been expressing serious concerns about birth control safety. Perhaps most important, women (many of whom were hearing about these serious side effects for the first time) began to unite.

Alice Wolfson became the face of the hearings after bringing them to a brief halt. Along with several other young feminists, she had come to the hearings with plans to protest the senators, who she felt weren’t really listening to the voices of women. However, after hearing the testimony of several doctors, she famously stood up in the chambers and shouted, “Why are 10 million women being used as guinea pigs!?”

She became fast friends with Barbara Seaman, whose book, The Doctor’s Case Against the Pill, helped launch the hearings. Ms. Seaman later wrote about the hearings saying it brought the “uptown” and “downtown” feminists together on the issue of birth control safety. She and Ms. Wolfson would go on to found the National Women’s Health Network. To this day, it is one of the nation’s top women’s health advocacy groups.

Shouldn’t Be Left (Alone)

With all of this organized opposition to The Pill, what did the hearings accomplish?

Well, The Pill became the first drug ever required to have a patient information booklet included in each pack. I suppose that would be pretty significant if it had been written in laymen terms so people could actually understand it.

And, the drug industry responded by releasing new, lower-dose formulations, which they claimed were safer. Unfortunately, their testing was even less stringent than it had been in the original trials. In fact, none of subsequent generations of hormonal birth control have been proven to be safe.

Clearly, what we as the opposition have done thus far hasn’t been enough. It’s time for more hearings. It’s time to hold the drug companies accountable for the sad state of women’s health. It doesn’t serve you or me – it doesn’t serve the Republicans or Democrats to have women suffering with chronic ailments or even dying in the name of birth control. In the end, it only serves the bottom line of Big Pharma. Maybe that’s what they’re referring to when they keep telling us ‘the benefits still outweigh the risks.’

#1
In the Name of The Pill

37 customer reviews

In the Name of The Pill*

by Mike Gaskins

The FDA approved The Pill despite it not being proven safe. Today, it has been linked to everything from blood clots and cancer to lupus and Crohn’s disease — and still has not been proven safe.
This book explores the medical and historical disconnects that brought us to this point.




 Price: $ 17.95

Buy now at Amazon*

Price incl. VAT., Excl. Shipping

Last updated on October 21, 2023 at 9:38 pm – Image source: Amazon Affiliate Program. All statements without guarantee.

We Need Your Help

More people than ever are reading Hormones Matter, a testament to the need for independent voices in health and medicine. We are not funded and accept limited advertising. Unlike many health sites, we don’t force you to purchase a subscription. We believe health information should be open to all. If you read Hormones Matter, like it, please help support it. Contribute now.

Yes, I would like to support Hormones Matter.

Image by Gerd Altmann from Pixabay

 

Lupus: Another Autoimmune Disease Linked to Birth Control

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Half a century ago, the National Institutes of Health sponsored a study on the metabolic effects of hormonal contraceptives. In the committee’s final report, Dr. Salhanick wrote:

“These accumulated data and others suggest that no tissue or organ system is free from a biological, functional, and/or morphological effect of contraceptive steroids.” [ NPH, Page 6567 ]

Fifty years later, the words of Dr. Noel Rose, the Father of Autoimmune Disease, rang with an eerie familiarity as he (almost proudly) proclaimed, “There is an autoimmune disease for every organ in the body.

Atypical Autoimmunity

There’s no such thing as a typical autoimmune disease (AI). Even in their commonalities they like to express their individuality. Like cousins determined to be different, each autoimmune disease has a unique relationship with estrogen. Researchers examining the differences in Multiple Sclerosis (MS) and Systemic Lupus Erythematosus (SLE) found that rising estrodiol levels create a protective effect in an MS patient, while it provokes and enhances flares in a lupus patient. They explained the complex distinctions this way:

“The effects of sex hormones (such as estrogens) on autoimmune diseases cannot be generalized and is context/disease-dependent. It is not surprising that the outcome of estrogen-mediated autoimmune responses is different among autoimmune diseases since estrogens affect all cells of the immune system, and the triggering and pathogenic mechanisms are varied among different diseases.”

Teams of scientists are just beginning to identify the complex stew of variables that contribute to AI diseases. Identification of the specific Tregs (a type of T-cell that modulates the immune system), cytokines (proteins that play an important role in cell signaling), and receptor cells (the soldier cells of the immune system) will help unlock the greatest mysteries of each AI disease. For now, researchers all seem to agree on one thing – estrogen affects EVERY cell in the immune system. One unfortunate stumbling block in this process is the generic use of the term ‘estrogen.’ The word is frequently used interchangeably to describe estradiol (estrogen produce naturally within the body) and the synthetic estrogens used in birth control or hormone replacement therapy. These synthetic molecules differ greatly from natural estradiol, and consequently, have very different affects on our immune systems. We can see the potential impact of synthetic estrogens by examining the evolution of lupus.

The Mysterious Evolution of Lupus

Imagine you are a rheumatologist. You developed a foundational understanding of lupus in medical school, but you really define lupus by what you have seen first-hand in your practice. Everything you know about the onset of disease, the typical patient, when it flares, and when it doesn’t is based on (and somewhat limited by) your time in practice.

Now, forget everything you know about lupus, and look at it through the eyes of a physician practicing in the late 60s.

Everything Dr. Giles Bole Jr. knew about lupus from his time in practice was being challenged. Events he had first classified as anomalies grew more frequent. Through conversations with concerned colleagues, he realized other doctors felt uneasy about birth control pills. Even some medical journals started doubting the ‘miracle pills’ that had been on the market for less than a decade. An editorial in the October 1969 edition of The Lancet said,

“The wisdom of administering such compounds to healthy women for many years must be seriously questioned.” [ NPH p. 6109]

Dr. Bole took up research that landed him before congress at the Nelson Pill Hearings in 1970. He described the phenomenon of young women contracting rheumatoid arthritis and “a much rarer disorder, Systemic Lupus Erythematosus.” He presented several examples of young women who developed symptoms within months of starting The Pill. In many cases, the symptoms reversed when the women stopped taking the synthetic hormones. Scientists at that time were already aware of certain medications causing Drug-Induced Lupus Erythematosus (DILE), but this was different because it was happening in young woman, and in many cases, the symptoms were irreversible.

These weren’t just isolated cases in Dr. Bole’s lab. Later in the hearings, Dr. Herbert Ratner estimated that one of every 2,000 birth control users developed lupus [NPH p. 6737]. Dr. Bole speculated that the synthetic compounds in birth control were to blame, saying that the ability to crossover between synthetic and natural hormones had limitations. He added, “I believe that it is clear to all of us that additional long-term studies relating to the biological effects of these compounds are extremely important.”

Lupus Today

A report published in Arthritis and Rheumatism in 1999 concluded that the incidence of lupus had tripled in the past forty years. An estimated 1.5 million people in the United States currently suffer from lupus (compared to 1.3 million with rheumatoid arthritis), and 90% of them are women. Clearly, something sparked this once rare disease.

In 2009, scientists from McGill University in Montreal released the results of a massive population study. They collected data on 1.7 million women, and found that women on oral contraceptives were 50% more likely to develop lupus. The greatest risk was in the first three months, when there was a 2.5-fold increased risk.

Overwhelming preliminary evidence points to a causal relationship with lupus. Unfortunately, we aren’t much closer to confirming the suspicions today than we were when Dr. Bole testified.

The State of Lupus Research

Instead of developing more extensive trials to investigate The Pill’s role in triggering lupus, researchers gave us the Safety of Estrogens in Lupus Erythematosus National Assessment (SELENA) trial, which resulted in the study director writing, “Should oral contraceptives be prescribed in SLE? In the last five years, we have come a long way. The answer today is frequently ‘yes’, whereas before, the answer was almost always ‘never.’”

The trial seemed to be designed for the sole purpose of reversing the answer to that question – to identify a new market of hormonal contraceptive users, a subset of SLE patients who could ‘safely’ take The Pill.

The trial’s summary claimed, “The results of the study will show whether it is safe for women with SLE to use the pill.”  This is a very broad statement given the selective group of 183 SLE patients who participated in the trial. To be included, investigators required a patient to have inactive or stable disease requiring less than 0.5 mg prednisone per kg of body weight per day over a 2-year period. They excluded patients with blood pressure higher than 145/95, any history of thrombosis, APL antibodies, hepatic dysfunction, diabetes, or complicated migraines. We’re talking about a very select group of healthy SLE patients being tested. Therefore, it is not surprising their trial concluded ‘that oral contraceptives do not increase the risk of flare among women with SLE whose disease is stable.’ Of course, for those so inclined, it is easy enough to drop the mitigating phrase from the end of that sentence and proclaim The Pill to be safe for SLE patients, period.

The Art of Deception

Studies like these muddy the waters. They give the impression that birth control won’t affect lupus, but read any lupus forum and you will find entries like this one:

“…At this point I decided to stop my birth control because I felt my body needed a break from medications. Within 6 months my hair was growing back, my fatigue went away, as well as the severe swelling. I was able to workout again and live my life! This was 4 years ago and I feel great. I still have flare ups, but it is not constant like it used to be. Recently I tried going on a different type of birth control (lowest hormone levels offered called Loestrin Fe) and had the same side effects within 8 months. I try to find info on birth control and lupus symptoms and how they correlate but have had no luck. Does anyone else have this problem or heard of birth control doing this? My doctor isn’t convinced that it is the birth control, but I think it is. Instead of taking me off the birth control, he is giving me anti-depressants to help me sleep so I’m not tired all the time.”

Let me take a moment to punctuate the absurdity of her situation. She went off The Pill, and her symptoms improved dramatically. Years later, she tried a new formulation of birth control, and the symptoms returned. BUT, her medical professional doesn’t think it’s The Pill. So, he’s prescribing anti-depressants instead!! I really wish I could say I’ve never heard anything like this before, but I have. And, I’ve heard variations of the scenario so frequently that I’m beginning to wonder if this is the new norm.

It doesn’t help when the website for the advocacy group, Lupus Foundation of America, contains information like this:

Many women have more lupus symptoms before menstrual periods and/or during pregnancy when estrogen production is high. This may indicate that estrogen somehow regulates the severity of lupus. However, no causal effect has been proven between estrogen, or any other hormone, and lupus. And, studies of women with lupus taking estrogen in either birth control pills or as postmenopausal therapy have shown no increase in significant disease activity.

No mention of the SLE needing to be stable – no mention of dangerous secondary symptoms to take into consideration – just straight up, “If you have lupus, The Pill is no cause for concern.” Doctors five years ago surely had some reason to tell lupus patients they should ‘never’ take The Pill.

It is true ‘no causal effect has been proven,’ but only because the drug manufacturers don’t want it to be proven. Look up virtually any illness that has been linked to birth control, and you will find someone friendly to the drug companies (and The Lupus Foundation certainly receives enough funding from drug companies to fall into this category) who throws out the ‘not proven’ argument. In his 1969 book, Pregnant or Dead, Dr. Harold Williams described how drug companies already employed this strategy to deny the link to serious thromboembolic issues:

“So long as the data presented could be claimed as “the best available” there was a ready-made defense for any hiatus in the data. As long as The Pill proponents expressed a desire for more complete data – all the while taking steps to thwart its compilation – they were safe…Then came the British. They reported preliminarily that a well-planned study was showing a distinctly higher incidence of thromboembolic disasters among Pill takers…This required some new strategy. Now it became necessary to try to discredit the British work, and at the same time to continue stalling studies in the United States that might yield similar results.” [Pregnant or Dead, pages 59-61]

What’s the Point?

By now, you may think the point of this article is that you can’t trust advocacy groups, the drug industry, or even your doctor, and, to an extent, I guess that’s true. But the most important point is this – trust your questions more than the answers. If an answer doesn’t ring true, you don’t have to accept it just because it came from your doctor, or some online expert.

I have spoken with women who were convinced their autoimmune disease must have been caused by The Pill… until they spoke with a doctor. Afterwards, they were convinced it was genetic. Of course, it’s genetic – estimates say that one in every four people carries a genetic variant that makes them more likely to develop an autoimmune disease [The Autoimmune Epidemic by Donna Jackson Nakazawa, page 71]. A patient must be genetically susceptible to acquire any AI disease, and perhaps some doctors are comfortable letting patients think it ends with genetics. However, environmental triggers that enter our body and mimic estradiol play a huge role in the actual activation of AI diseases like lupus.

Listen to your body. If it tells you that something doesn’t ‘feel right’ about your hormonal contraceptive, pay attention even if your doctor acts like it’s nothing (especially if he/she suggests anti-depressants as the solution).

Trust your questions more than the answers.

#1
In the Name of The Pill

37 customer reviews

In the Name of The Pill*

by Mike Gaskins

The FDA approved The Pill despite it not being proven safe. Today, it has been linked to everything from blood clots and cancer to lupus and Crohn’s disease — and still has not been proven safe.
This book explores the medical and historical disconnects that brought us to this point.




 Price: $ 17.95

Buy now at Amazon*

Price incl. VAT., Excl. Shipping

Last updated on October 21, 2023 at 9:38 pm – Image source: Amazon Affiliate Program. All statements without guarantee.

We Need Your Help

More people than ever are reading Hormones Matter, a testament to the need for independent voices in health and medicine. We are not funded and accept limited advertising. Unlike many health sites, we don’t force you to purchase a subscription. We believe health information should be open to all. If you read Hormones Matter, like it, please help support it. Contribute now.

Yes, I would like to support Hormones Matter.

 

Vitamin D3 and Lupus

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The untimely death of 23-year-old Sasha McHale, daughter of professional basketball’s Hall of Famer Kevin McHale, recently shocked the world.

Sasha inherited her father’s athleticism, energy, enthusiasm for life, and love of the northern U.S. state of Minnesota. An insidious disease called lupus prematurely snatched Sasha from her family, friends, and life.

Lupus is a chronic autoimmune disease that attacks the body’s cells, tissues, and organs, and results in severe inflammation, fatigue, and, in some cases, death. The medical name for the most common form of the lupus is “systemic lupus erythematosus” (SLE). According to the Lupus Foundation of America, about 1.5 million Americans, and over five million people globally, suffer from a form of lupus. Ninety percent of persons diagnosed with the disease are women, many of whom are in their child-bearing years.

Mounting evidence suggests adequate vitamin D3 in the body may protect against the development of autoimmune diseases including lupus. Genetic and environmental factors including vitamin D3 deficiency have been linked to lupus. Sensitivity to sunlight, the primary source of vitamin D3, is common among SLE patients. Scientific research indicates a high prevalence of vitamin D3 deficiency among people suffering SLE:

Researchers at the University of Toronto Lupus Clinic studied 124 female SLE patients to understand, inter alia, their circulating vitamin D3 levels. Eighty-four percent of the women had vitamin D3 blood serum levels less than a sub-optimal reading of 32 ng/mL.

The Medical University of South Carolina conducted a study of vitamin D3 blood serum levels of 123 individuals who had been recently diagnosed with SLE. The findings suggested vitamin D3 deficiency as a possible risk factor for SLE.

Researchers studied 25 Canadian women diagnosed with SLE and found that over half of these patients had less than 20 ng/mL of vitamin D3 circulating in their blood. The research also suggested that hydroxychloroquine (HCQ), a drug used to treat SLE, may inhibit vitamin D3 production.

A study published in a 2012 edition of the journal Dermato-Endocrinology not only documented the prevalence of low vitamin D3 in SLE patients but recommended oral vitamin D3 supplementation for SLE patients. The researchers lauded the safety, low cost, and wide availability of vitamin D3 supplements as well as their potential effectiveness against SLE progression.

Maintaining adequate vitamin D3 levels may forestall the development of autoimmune diseases including lupus. In addition, vitamin D3’s capability to reduce inflammation may alleviate lupus symptoms. Further research is required to confirm the extent of vitamin D3’s connection with lupus.

Copyright ©2012 by Susan Rex Ryan
All rights reserved.

Autoimmune Olympiads

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Well, the Olympics are over. Thank God! Now I can get some sleep. I was so sleep deprived. I could have won a gold medal in crankiness.

I am in awe when I see the super-human type feats executed by these athletes. And then, when I hear that some of these competitors have autoimmune diseases like me, it is astounding.

Diseased Olympiads…what an oxymoron.

But it just goes to show you, no one is immune to the auto-immune atrocities.

These athletes endure their body fighting itself, yet they practice multiple hours in a day. When I am on my third or fourth dream all snugly in my bed, they are waking up before the sun comes up to begin their training. Just can’t wrap my mind around that…

Here are a few of those ailing athletes who competed at this year’s 2012 Olympics in London:

Tennis -Venus Williams–Sjogren’s syndrome (The body attacks moisture producing glands) Advanced to the third round of the London Olympics.

Kayaking –Carrie Johnson-Crohn’s disease (Inflammation of the digestive tract) Advanced to the semifinals.

Soccer (or women’s football)-Shannon Box-Lupus (the body attacks healthy tissues) Won a Gold medal.

Track and Field-Sanya Richards-Ross-Behcet’s Syndrome (Vasculitis leading to ulcers particularly around the mouth, genitals and pupils) Two-time gold medal winner in London.

Track and Field, pole vaulting-Jenn Suhr-Celiac’s disease (hypersensitivity to gluten) Won gold medal.

All of them deserve the gold medal as far as I am concerned.

This article was originally posted on http://www.crazythyroidlady.blogspot.com and was re-posted with permission.